Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | F2R | P25116 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10841460 | 0.93 | L3MBTL1 (0.48) | MAPTHRH4HRH3L3MBTL1F2RL3 | |
| SCHEMBL19036232 | 0.73 | HRH4 (0.54) | MAPTHRH4HRH3LMNAALDH1A1 | |
| SCHEMBL11706515 | 0.71 | L3MBTL1 (0.57) | MAPTPOLBL3MBTL1F2RL3NPSR1 | |
| SCHEMBL11200693 | 0.68 | ALDH1A1 (0.52) | MAPTL3MBTL1THRBTDP1SMN1; SMN2 | |
| SCHEMBL10841737 | 0.68 | THRB (0.61) | MAPTPOLBL3MBTL1NPSR1THRB | |
| SCHEMBL16435341 | 0.67 | TSHR (0.58) | MAPTTHRBTDP1SMN1; SMN2KMT2A | |
| SCHEMBL9038869 | 0.66 | POLB (0.58) | POLBHRH4HRH3KMT2AMEN1 | |
| SCHEMBL18394407 | 0.66 | CASP3 (0.47) | MAPTPOLBNPSR1SMN1; SMN2LMNA | |
| SCHEMBL11202002 | 0.65 | TSHR (0.51) | MAPTTHRBTDP1SMN1; SMN2KMT2A | |
| SCHEMBL23576822 | 0.65 | ABCG2 (0.47) | MAPTHRH4HRH3L3MBTL1F2RL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174833-A2 | Triazoloquinoline derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |