Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.40 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.40 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10843980 | 0.83 | HRH4 (0.38) | GAAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL10844524 | 0.82 | ATM (0.43) | GAAPDE10A | |
| SCHEMBL10852463 | 0.79 | HSD17B10 (0.37) | ARGAAEGLN1OPRL1 | |
| SCHEMBL10844658 | 0.78 | ALDH1A1 (0.36) | GAALMNAOPRL1 | |
| SCHEMBL10850313 | 0.77 | HSD17B10 (0.61) | GAAHTT | |
| SCHEMBL10846080 | 0.77 | GAA (0.47) | GAA | |
| SCHEMBL29770350 | 0.76 | AR (0.45) | ARGAAHTTPRKAG1PRKAA2 | |
| SCHEMBL27203431 | 0.76 | AR (0.45) | ARGAAHTTPRKAG1PRKAA2 | |
| SCHEMBL10849255 | 0.76 | L3MBTL1 (0.57) | GAALMNA | |
| SCHEMBL10847830 | 0.75 | ALDH1A1 (0.34) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4608381-A | ANTIARTHRITIC AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1986-08-26 | — | — | US | claimed |
| US-4608381-A | ANTIARTHRITIC AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1986-08-26 | — | — | US | disclosed |