Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | FABP6 | P51161 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10844524 | 0.90 | ATM (0.43) | HSD17B10GAACYP2C9MEN1KMT2A | |
| SCHEMBL19886227 | 0.80 | HSD17B10 (0.42) | HSD17B10GAACYP2C9MEN1KMT2A | |
| SCHEMBL10850313 | 0.80 | HSD17B10 (0.61) | HSD17B10GAACYP2C9KMT2AKDM4E | |
| SCHEMBL10846080 | 0.80 | GAA (0.47) | HSD17B10GAACYP2C9ENPP1MEN1 | |
| SCHEMBL10845706 | 0.79 | AR (0.48) | GAAOPRL1EGLN1AR | |
| SCHEMBL10844658 | 0.78 | ALDH1A1 (0.36) | HSD17B10GAAOPRL1ENPP1TDP1 | |
| SCHEMBL10847830 | 0.75 | ALDH1A1 (0.34) | HSD17B10GAAENPP1MEN1KMT2A | |
| SCHEMBL10843980 | 0.74 | HRH4 (0.38) | GAAOPRL1ENPP1KMT2ATDP1 | |
| SCHEMBL10849255 | 0.73 | L3MBTL1 (0.57) | HSD17B10GAAMEN1KMT2AMAPT | |
| SCHEMBL10846974 | 0.69 | HRH4 (0.48) | HSD17B10GAAOPRL1CYP2C9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4608381-A | ANTIARTHRITIC AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1986-08-26 | — | — | US | disclosed |