Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 3/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10846080 | 0.84 | GAA (0.47) | ALDH1A1TP53L3MBTL1ENPP1KDM4E | |
| SCHEMBL10843980 | 0.84 | HRH4 (0.38) | ALDH1A1TP53L3MBTL1ENPP1OPRL1 | |
| SCHEMBL10847830 | 0.82 | ALDH1A1 (0.34) | ALDH1A1TP53L3MBTL1ENPP1KDM4E | |
| SCHEMBL10849255 | 0.81 | L3MBTL1 (0.57) | ALDH1A1TP53L3MBTL1KDM4EHSD17B10 | |
| SCHEMBL10845706 | 0.78 | AR (0.48) | OPRL1GAALMNA | |
| SCHEMBL10844524 | 0.78 | ATM (0.43) | KDM4EHSD17B10GAAHPGDTDP1 | |
| SCHEMBL10852463 | 0.78 | HSD17B10 (0.37) | ENPP1KDM4EOPRL1HSD17B10GAA | |
| SCHEMBL16134491 | 0.77 | L3MBTL1 (0.60) | ALDH1A1L3MBTL1KDM4EHSD17B10PDE3B | |
| SCHEMBL10850313 | 0.76 | HSD17B10 (0.61) | ALDH1A1TP53KDM4EHSD17B10GAA | |
| SCHEMBL26639273 | 0.73 | ATP4A (0.48) | ALDH1A1KDM4EHSD17B10GAAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4608381-A | ANTIARTHRITIC AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1986-08-26 | — | — | US | claimed |
| US-4608381-A | ANTIARTHRITIC AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1986-08-26 | — | — | US | disclosed |