Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SQSTM1 | Q13501 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29415266 | 0.84 | GAA (0.39) | TSHRSMN1; SMN2ALDH1A1LMNATP53 | |
| SCHEMBL778991 | 0.84 | GAA (0.39) | TSHRSMN1; SMN2ALDH1A1LMNATP53 | |
| SCHEMBL18770158 | 0.80 | ACLY (0.41) | SMN1; SMN2ALDH1A1LMNATP53HTT | |
| SCHEMBL16044696 | 0.75 | MYC (0.41) | TSHRSMN1; SMN2ALDH1A1LMNACA9 | |
| SCHEMBL10846783 | 0.75 | TRPV4 (0.37) | TSHRSMN1; SMN2ALDH1A1LMNATP53 | |
| SCHEMBL7236099 | 0.75 | GAA (0.52) | ALDH1A1LMNACA9CA12CA1 | |
| SCHEMBL8713487 | 0.74 | HTR6 (0.53) | SMN1; SMN2ALDH1A1CA9CA12CA1 | |
| SCHEMBL10042818 | 0.73 | TSHR (0.46) | TSHRLMNAHTTCASP1 | |
| SCHEMBL8712194 | 0.73 | HSD11B1 (0.43) | TSHRALDH1A1HTTNFE2L2HTR6 | |
| SCHEMBL582357 | 0.73 | KMT2A (0.44) | SMN1; SMN2ALDH1A1LMNAHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4619688-A | Herbicidal sulfonylguanidine derivatives | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-28 | — | — | US | disclosed |
| EP-0148498-A1 | Sulfonylguanidine derivatives | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-07-17 | — | — | EP | disclosed |