Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.54 |
| ▸ | PTAFR | P25105 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 5/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.44 |
| ▸ | HTR2A | P28223 | 4/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.44 |
| ▸ | HRH1 | P35367 | 4/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.44 |
| ▸ | HTR2B | P41595 | 4/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.44 |
| ▸ | DRD3 | P35462 | 4/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.44 |
| ▸ | HTR7 | P34969 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10962757 | 0.99 | SETD7 (0.55) | SETD7PTAFRMEN1KMT2AMAPT | |
| SCHEMBL10962040 | 0.85 | CHRM2 (0.57) | SETD7MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL10961042 | 0.83 | ADRA2A (0.58) | SETD7MEN1KMT2AMAPK1DRD2 | |
| SCHEMBL9718818 | 0.82 | SETD7 (0.51) | SETD7PTAFRMEN1KMT2AMAPT | |
| SCHEMBL10846771 | 0.81 | HRH1 (0.57) | MEN1KMT2AMAPTMAPK1SMN1; SMN2 | |
| Etolotifen SCHEMBL2109044 | 0.81 | DRD3 (0.68) | SETD7MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL10847545 | 0.81 | PTAFR (0.44) | SETD7PTAFRMEN1KMT2AMAPT | |
| Etolotifen SCHEMBL10851254 | 0.80 | DRD3 (0.67) | SETD7MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL10848583 | 0.80 | DRD3 (0.52) | SETD7MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL10848598 | 0.80 | DRD3 (0.52) | SETD7MEN1KMT2AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4609664-A | ANTIALLERGIC | SANDOZ LTD. (CH) | 1986-09-02 | — | — | US | claimed |
| EP-0047226-B1 | PIPERIDYLIDENE DERIVATIVES, THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANDOZ AG (CH) | 1985-05-15 | — | — | EP | claimed |
| EP-0047226-A2 | Piperidylidene derivatives, their production and pharmaceutical compositions containing them | SANDOZ AG (CH) | 1982-03-10 | — | — | EP | claimed |
| US-4609664-A | ANTIALLERGIC | SANDOZ LTD. (CH) | 1986-09-02 | — | — | US | disclosed |
| EP-0047226-B1 | PIPERIDYLIDENE DERIVATIVES, THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANDOZ AG (CH) | 1985-05-15 | — | — | EP | disclosed |
| EP-0047226-A2 | Piperidylidene derivatives, their production and pharmaceutical compositions containing them | SANDOZ AG (CH) | 1982-03-10 | — | — | EP | disclosed |