Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NGLY1 | Q96IV0 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | CLK2 | P49760 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.38 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10844579 | 0.83 | ATM (0.46) | SLC2A1MAPTALDH1A1HPGDGAA | |
| SCHEMBL10801863 | 0.79 | SLC2A1 (0.70) | SLC2A1MAPTKDM4EGAASMN1; SMN2 | |
| SCHEMBL10840308 | 0.75 | SLC2A1 (0.65) | SLC2A1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL10847105 | 0.72 | GPR35 (0.41) | ALDH1A1HPGDHSD17B10ALOX15MGAM | |
| SCHEMBL10804527 | 0.71 | TGFBR1 (0.53) | SLC2A1AURKASYK | |
| SCHEMBL10840466 | 0.69 | SLC2A1 (0.70) | SLC2A1MAPTKDM4EGAAAURKA | |
| SCHEMBL10840031 | 0.68 | SLC2A1 (0.59) | SLC2A1MAPTGFERGAASYK | |
| SCHEMBL10805234 | 0.68 | SLC2A1 (0.74) | SLC2A1MAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL11577556 | 0.67 | GLA (0.54) | MAPTROCK1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL31633788 | 0.67 | KDM4E (0.51) | MAPTGFERNGLY1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154220-A2 | Pyrazolopyridine derivatives | BEECHAM GROUP PLC (GB) | 1985-09-11 | — | — | EP | claimed |
| US-4621089-A | Pyrazolopyridine derivatives and their use in treating inflammation and allergic conditions | BEECHAM GROUP P.L.C. (GB) | 1986-11-04 | — | — | US | disclosed |
| EP-0154220-A2 | Pyrazolopyridine derivatives | BEECHAM GROUP PLC (GB) | 1985-09-11 | — | — | EP | disclosed |