Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10846891 | 0.81 | PRMT6 (0.50) | PRMT6KMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL705421 | 0.81 | ALDH1A1 (0.53) | PRMT6KMT2AMEN1POLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL11475500 | 0.80 | PRMT6 (0.49) | PRMT6KMT2AMEN1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL10746854 | 0.80 | ALDH1A1 (0.51) | PRMT6KMT2APOLBALDH1A1MAPT | |
| SCHEMBL10851079 | 0.78 | POLB (0.47) | PRMT6KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL10857640 | 0.77 | PRMT6 (0.51) | PRMT6CHRM2BCHEACHE | |
| SCHEMBL11360362 | 0.77 | PRMT6 (0.55) | PRMT6CHRM2BCHEACHE | |
| SCHEMBL11463439 | 0.75 | PRMT6 (0.50) | PRMT6BCHEACHE | |
| SCHEMBL11209167 | 0.75 | PRMT6 (0.50) | PRMT6BCHEACHE | |
| SCHEMBL10741444 | 0.75 | PRMT6 (0.61) | PRMT6BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4571398-A | Cytosine derivatives having histamine H2 -antagonist activity | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1986-02-18 | — | — | US | disclosed |
| US-4567176-A | HISTAMINE H2-ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1986-01-28 | — | — | US | disclosed |