Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 8/20 | 0.71 |
| ▸ | ALPI | P09923 | 8/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | CA2 | P00918 | 3/20 | 0.64 |
| ▸ | STS | P08842 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13930283 | 0.89 | MAOB (0.71) | ALPLALPIKDM4EALDH1A1GAA | |
| SCHEMBL10850733 | 0.87 | MAOB (0.70) | ALPLALPIKDM4EALDH1A1GAA | |
| SCHEMBL10848973 | 0.85 | ALPL (0.63) | ALPLALPIKDM4EALDH1A1GAA | |
| SCHEMBL137684 | 0.84 | ALPL (0.78) | ALPLALPIKDM4EALDH1A1GAA | |
| SCHEMBL10850528 | 0.84 | ALPL (0.86) | ALPLALPISTSHPGDMAOB | |
| SCHEMBL25184 | 0.81 | ALDH1A1 (0.76) | ALPLALPIKDM4EALDH1A1GAA | |
| SCHEMBL30139608 | 0.81 | ALDH1A1 (0.76) | ALPLALPIKDM4EALDH1A1GAA | |
| Potassium Ion SCHEMBL380405 | 0.80 | KDM4E (0.74) | ALPLALPIKDM4EALDH1A1GAA | |
| SCHEMBL3761326 | 0.80 | ALDH1A1 (0.74) | ALPLALPIKDM4EALDH1A1GAA | |
| SCHEMBL3761324 | 0.80 | KDM4E (0.74) | ALPLALPIKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4618622-A | ANTIDEPRESSANTS, ANTIALLERGENS | BASF AKTIENGESELLSCHAFT (DE) | 1986-10-21 | — | — | US | disclosed |