Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10849390 | 1.00 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1MAPTGAA | |
| SCHEMBL9813725 | 0.92 | KMT2A (0.43) | ALDH1A1KMT2AMEN1MAPTGAA | |
| SCHEMBL10852036 | 0.92 | KMT2A (0.43) | ALDH1A1KMT2AMEN1MAPTGAA | |
| SCHEMBL9813569 | 0.83 | PSMD14 (0.61) | ALDH1A1KMT2AMEN1MAPTGAA | |
| SCHEMBL9813566 | 0.83 | PSMD14 (0.61) | ALDH1A1KMT2AMEN1MAPTGAA | |
| SCHEMBL9813563 | 0.81 | LMNA (0.49) | ALDH1A1KMT2AMAPTTDP1PSMD14 | |
| SCHEMBL9813560 | 0.81 | LMNA (0.49) | ALDH1A1KMT2AMAPTTDP1PSMD14 | |
| SCHEMBL9813588 | 0.80 | LMNA (0.45) | ALDH1A1KMT2AMEN1MAPTTDP1 | |
| SCHEMBL9813583 | 0.80 | LMNA (0.45) | ALDH1A1KMT2AMEN1MAPTTDP1 | |
| SCHEMBL9813556 | 0.77 | MAPK1 (0.44) | ALDH1A1KMT2AMEN1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4563471-A | CENTRAL NERVOUS SYSTEM DISORDERS | WARNER-LAMBERT COMPANY (US) | 1986-01-07 | — | — | US | disclosed |