Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 9/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.49 |
| ▸ | QPCT | Q16769 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10852436 | 0.99 | TBXAS1 (0.63) | TBXAS1MEN1LMNAKMT2APOLB | |
| SCHEMBL18457438 | 0.83 | QPCT (0.56) | TBXAS1POLBNPC1QPCT | |
| Hydrochloric Acid SCHEMBL10851015 | 0.80 | ALDH1A1 (0.65) | TBXAS1MEN1KMT2APOLBNPC1 | |
| Hydrochloric Acid SCHEMBL10857301 | 0.77 | TBXAS1 (0.43) | TBXAS1MEN1LMNAKMT2APOLB | |
| SCHEMBL15854270 | 0.77 | ALDH1A1 (0.67) | TBXAS1MEN1LMNAKMT2A | |
| SCHEMBL5350770 | 0.77 | TBXAS1 (1.00) | TBXAS1MEN1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL17219474 | 0.76 | ALDH1A1 (0.65) | TBXAS1MEN1LMNAKMT2APOLB | |
| Hydrochloric Acid SCHEMBL17219469 | 0.76 | ALDH1A1 (0.65) | TBXAS1MEN1LMNAKMT2APOLB | |
| Hydrochloric Acid SCHEMBL11474904 | 0.75 | TBXAS1 (1.00) | TBXAS1MEN1LMNAKMT2A | |
| Dazoxiben SCHEMBL11554 | 0.75 | TBXAS1 (1.00) | TBXAS1MEN1LMNAKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4632934-A | THROMBOXANE SYNTHETASE INHIBITORS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1986-12-30 | — | — | US | disclosed |