Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 4/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.54 |
| ▸ | SOD1 | P00441 | 2/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.51 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11495035 | 0.90 | SOD1 (0.67) | QPCTCYP19A1SOD1NPC1RAB9A | |
| SCHEMBL10852247 | 0.83 | TBXAS1 (0.62) | QPCTTBXAS1POLBNPC1 | |
| SCHEMBL9565898 | 0.82 | CYP11B1 (0.55) | QPCTCYP19A1SOD1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL10852436 | 0.82 | TBXAS1 (0.63) | QPCTTBXAS1POLBMAPTNPC1 | |
| SCHEMBL13164564 | 0.82 | CYP1A2 (0.56) | QPCTCYP11B1CYP11B2CYP1A2POLB | |
| SCHEMBL25039563 | 0.81 | KMT2A (0.58) | QPCTSOD1CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL4173553 | 0.81 | QPCT (0.60) | QPCTCYP19A1SOD1TBXAS1CACNA1B | |
| SCHEMBL4939445 | 0.79 | QPCT (0.52) | QPCTCYP19A1SOD1CYP11B1CYP11B2 | |
| SCHEMBL5551707 | 0.79 | SOD1 (0.53) | QPCTSOD1CYP11B1TBXAS1NPC1 | |
| SCHEMBL27713606 | 0.77 | ALDH1A1 (0.54) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200109139-A1 | PYRIMIDINE COMPOUND AND MEDICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2020-04-09 | — | — | US | disclosed |
| US-20170029418-A1 | PYRIMIDINE COMPOUND AND MEDICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2017-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170029418-A1 | PYRIMIDINE COMPOUND AND MEDICAL USE THEREOF | TYMP, TYMS, DPYD | QPCT 1030/4885CYP19A1 1141/4885SOD1 4106/4885 |
| US-20200109139-A1 | PYRIMIDINE COMPOUND AND MEDICAL USE THEREOF | TYMP, TYMS, DPYD | QPCT 1030/4885CYP19A1 1141/4885SOD1 4106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.