SCHEMBL10857014

SCHEMBL10857014

Cc1cc(C)cc(COS(=O)(O)=S)c1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 1/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 2/20 0.39
CA1 P00915 1/20 0.39
TACR1 P25103 6/20 0.35
FFAR1 O14842 1/20 0.35
FFAR4 Q5NUL3 1/20 0.35
ALDH1A1 P00352 2/20 0.34
PGK1 P00558 1/20 0.34
PGK2 P07205 1/20 0.34
IDH1 O75874 1/20 0.33
IDO1 P14902 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9861770 0.82 IDO1 (0.56) FFAR4ALDH1A1IDO1
SCHEMBL9861366 0.82 CA1 (0.34) PARP10CA2CA9CA1FFAR1
SCHEMBL9861023 0.81 CA2 (0.61) PARP10CA2CA9CA1ALDH1A1
SCHEMBL10501977 0.77 CA2 (0.54) CA2CA9CA1IDO1CYP3A4
SCHEMBL9861379 0.77 CA2 (0.56) PARP10CA2CA9CA1ALDH1A1
SCHEMBL9861010 0.77 GABRA1 (0.41) TACR1ALDH1A1IDO1
SCHEMBL14430286 0.74 CA2 (0.42) PARP10CA2CA9CA1TACR1
SCHEMBL9861765 0.73 CA2 (0.45) CA2CA9CA1ALDH1A1
SCHEMBL5078811 0.72 CA2 (0.59) CA2CA9CA1ALDH1A1IDO1
SCHEMBL27464853 0.71 CA2 (0.57) CA2CA9CA1ALDH1A1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4581297-A STEEL BELTED RADIAL TIRES MONSANTO EUROPE, S.A. (BE) 1986-04-08 US disclosed
EP-0150168-A2 Use of metal salts of thiosulphuric -S-esters as rubber/metal bonding promoters MONSANTO EUROPE S.A./N.V. (BE) 1985-07-31 EP disclosed