SCHEMBL9861366

SCHEMBL9861366

CCc1ccc(C)c(COS(=O)(O)=S)c1.Cc1cc(C)cc(COS(=O)(O)=S)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
FFAR1 O14842 1/20 0.34
FFAR4 Q5NUL3 1/20 0.34
PARP10 Q53GL7 1/20 0.32
ALOX5 P09917 1/20 0.32
PTGS1 P23219 1/20 0.32
PTGS2 P35354 1/20 0.32
NPC1 O15118 1/20 0.32
SLC5A2 P31639 1/20 0.31
MAPT P10636 2/20 0.31
HTT P42858 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
GAA P10253 1/20 0.31
AGTR1 P30556 1/20 0.31
PKM P14618 1/20 0.31
RAPGEF4 Q8WZA2 1/20 0.31
NR3C1 P04150 1/20 0.30
PGR P06401 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10859458 0.92 PKM (0.35) CA1CA2CA9ALOX5PTGS1
SCHEMBL10857014 0.82 PARP10 (0.39) CA1CA2CA9FFAR1FFAR4
SCHEMBL9860933 0.81 TRPA1 (0.35) CA2CA9NPC1MAPTL3MBTL1
SCHEMBL9861765 0.75 CA2 (0.45) CA1CA2CA9NPC1MAPT
SCHEMBL9861023 0.72 CA2 (0.61) CA1CA2CA9PARP10NPC1
SCHEMBL9861770 0.70 IDO1 (0.56) FFAR4
SCHEMBL10501977 0.70 CA2 (0.54) CA1CA2CA9
SCHEMBL9861379 0.68 CA2 (0.56) CA1CA2CA9PARP10NPC1
SCHEMBL5498171 0.68 TRPA1 (0.44) CA2ALOX5PTGS1PTGS2NPC1
SCHEMBL169507 0.68 TRPA1 (0.44) CA2ALOX5PTGS1PTGS2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0150168-B1 USE OF METAL SALTS OF THIOSULPHURIC -S-ESTERS AS RUBBER/METAL BONDING PROMOTERS MONSANTO EUROPE S.A./N.V. (BE) 1991-05-08 EP disclosed