Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | HMGCR | P04035 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.35 |
| ▸ | RXRB | P28702 | 2/20 | 0.35 |
| ▸ | RXRG | P48443 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9860969 | 0.83 | NR4A2 (0.45) | RXRARXRBTRPV1 | |
| SCHEMBL10857014 | 0.77 | PARP10 (0.39) | IDO1ALDH1A1TACR1 | |
| SCHEMBL10501977 | 0.73 | CA2 (0.54) | IDO1 | |
| SCHEMBL9861045 | 0.72 | SHBG (0.51) | RXRARXRB | |
| SCHEMBL5964958 | 0.71 | GABRA1 (0.52) | GABRA1GABRB2HMGCRRXRARXRB | |
| SCHEMBL1789187 | 0.71 | GABRA1 (0.46) | GABRA1GABRB2HMGCRRXRARXRB | |
| SCHEMBL19022182 | 0.70 | IDO1 (0.34) | GABRA1GABRB2HMGCRIDO1TACR1 | |
| SCHEMBL9861765 | 0.69 | CA2 (0.45) | RXRARXRBALDH1A1 | |
| SCHEMBL9861023 | 0.69 | CA2 (0.61) | ALDH1A1 | |
| SCHEMBL1789188 | 0.69 | GABRA1 (0.45) | GABRA1GABRB2HMGCRRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150168-B1 | USE OF METAL SALTS OF THIOSULPHURIC -S-ESTERS AS RUBBER/METAL BONDING PROMOTERS | MONSANTO EUROPE S.A./N.V. (BE) | 1991-05-08 | — | — | EP | disclosed |
| US-4581297-A | STEEL BELTED RADIAL TIRES | MONSANTO EUROPE, S.A. (BE) | 1986-04-08 | — | — | US | disclosed |
| EP-0150168-A2 | Use of metal salts of thiosulphuric -S-esters as rubber/metal bonding promoters | MONSANTO EUROPE S.A./N.V. (BE) | 1985-07-31 | — | — | EP | disclosed |