Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146130 | 0.89 | PTPN1 (0.63) | PTPN1CES2CES1ERCC5FEN1 | |
| Hydrochloric Acid SCHEMBL6744118 | 0.87 | PTPN1 (0.61) | PTPN1CES2CES1ERCC5FEN1 | |
| Formic Acid SCHEMBL28074373 | 0.82 | PTPN1 (0.55) | PTPN1CES2CES1ERCC5FEN1 | |
| SCHEMBL8841074 | 0.82 | CES2 (0.54) | PTPN1CES2CES1ERCC5FEN1 | |
| SCHEMBL17593327 | 0.75 | CES2 (0.46) | PTPN1CES2CES1ERCC5FEN1 | |
| SCHEMBL13656481 | 0.74 | CES2 (0.56) | PTPN1CES2CES1ERCC5FEN1 | |
| SCHEMBL23069153 | 0.74 | CES2 (0.58) | PTPN1CES2CES1ERCC5FEN1 | |
| SCHEMBL8066142 | 0.73 | KDM4E (0.46) | PTPN1CES2CES1ERCC5FEN1 | |
| SCHEMBL4820037 | 0.72 | CES2 (0.56) | PTPN1CES2CES1ERCC5FEN1 | |
| SCHEMBL245406 | 0.72 | CES2 (0.56) | PTPN1CES2CES1ERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4577014-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1986-03-18 | — | — | US | disclosed |
| US-4501739-A | BACTERICIDES, ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1985-02-26 | — | — | US | disclosed |
| US-4406898-A | ANTIBIOTICS CONTAINING A THIENOPYRIDINIUM OR FUROPYRIDINIUM GROUP | ELI LILLY AND COMPANY (US) | 1983-09-27 | — | — | US | disclosed |
| EP-0074268-A2 | Improvements in or relating to thieno and furopyridinium-substituted cephalosporin derivatives | ELI LILLY AND COMPANY (US) | 1983-03-16 | — | — | EP | disclosed |
| US-4071630-A | ANGINA PECTORIS | SANDOZ LTD. (CH) | 1978-01-31 | — | — | US | disclosed |
| US-3998835-A | HYPERLIPOIDEMIA AND HYPERGLYCEMIA INHIBITORS, ANTIARRYHTHMIC AGENTS | SANDOZ LTD. (CH) | 1976-12-21 | — | — | US | disclosed |