Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 7/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9670330 | 0.83 | DAO (0.35) | DAOADRA1AKMT2AMEN1TDP1 | |
| SCHEMBL11300207 | 0.70 | DAO (0.37) | DAOKMT2AMEN1TDP1POLB | |
| SCHEMBL4603182 | 0.64 | KDM4E (0.44) | KMT2AMEN1TDP1KDM4EALDH1A1 | |
| SCHEMBL17055847 | 0.61 | KDM4E (0.53) | KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL23285670 | 0.60 | ADRA1A (0.38) | DAOADRA1AKDM4EHPGD | |
| SCHEMBL10813055 | 0.60 | HPGD (0.37) | TDP1HPGDHSD17B10 | |
| Ether SCHEMBL6106398 | 0.57 | ALDH1A1 (0.35) | KMT2AMEN1TDP1POLBALDH1A1 | |
| Ether SCHEMBL11311505 | 0.57 | TSHR (0.42) | KMT2AMEN1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL19055623 | 0.56 | KDM4E (0.47) | KMT2ATDP1POLBKDM4EALDH1A1 | |
| SCHEMBL20599912 | 0.55 | TYMP (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0180897-A2 | 5-Fluorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-14 | — | — | EP | disclosed |
| EP-0180188-A2 | A composition for increasing the anti-cancer activity of an anti-cancer compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-07 | — | — | EP | disclosed |