Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | PPOX | P50336 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10852632 | 0.86 | TDP1 (0.60) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10856547 | 0.83 | TDP1 (0.61) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10850417 | 0.83 | MEN1 (0.53) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10856940 | 0.77 | TDP1 (0.43) | TDP1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL11282021 | 0.77 | MEN1 (0.71) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10854190 | 0.77 | MAPT (0.55) | TDP1MEN1KMT2ATTRMAPT | |
| SCHEMBL10858848 | 0.77 | TDP1 (0.43) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10854561 | 0.76 | ALDH1A1 (0.42) | TDP1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL10851478 | 0.75 | LMNA (0.49) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10853087 | 0.75 | MEN1 (0.58) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4563310-A | HERBICIDES | ZOECON CORPORATION (US) | 1986-01-07 | — | — | US | disclosed |
| EP-0065374-A1 | Substituted phosphinates and phosphinothioates and their use for the control of weeds | ZOECON CORPORATION (US) | 1982-11-24 | — | — | EP | disclosed |