Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | NQO2 | P16083 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | FSHR | P23945 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17119519 | 0.77 | KDM4E (0.43) | MTNR1AMTNR1BNQO2HTR6KDM4E | |
| SCHEMBL19009430 | 0.74 | HTR6 (0.41) | MTNR1AMTNR1BNQO2HTR6ALDH1A1 | |
| SCHEMBL7926119 | 0.74 | HTR6 (0.43) | MTNR1AMTNR1BNQO2HTR6KDM4E | |
| SCHEMBL14189740 | 0.74 | ALDH1A1 (0.44) | MTNR1AMTNR1BNQO2HTR6KCNN4 | |
| SCHEMBL16081546 | 0.72 | ALDH1A1 (0.46) | MTNR1AMTNR1BNQO2HTR6ALDH1A1 | |
| SCHEMBL2338975 | 0.72 | HTR6 (0.56) | MTNR1AMTNR1BNQO2HTR6 | |
| SCHEMBL31121639 | 0.72 | HTR6 (0.56) | MTNR1AMTNR1BNQO2HTR6 | |
| SCHEMBL27521030 | 0.71 | HTR6 (0.41) | MTNR1AMTNR1BNQO2HTR6ALDH1A1 | |
| SCHEMBL15114726 | 0.71 | HTR6 (0.46) | MTNR1AMTNR1BNQO2HTR6KDM4E | |
| SCHEMBL6130641 | 0.71 | HTR6 (0.46) | MTNR1AMTNR1BNQO2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4594432-A | Process for the synthesis of 1α,23(S),25-trihydroxycholecalciferol and 1α,23(R),25-trihydroxycholecalciferol | HOFFMAN-LA ROCHE INC. (US) | 1986-06-10 | — | — | US | disclosed |