Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | DUSP10 | Q9Y6W6 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16081546 | 0.83 | ALDH1A1 (0.46) | HTR6MTNR1AMTNR1BALDH1A1NQO2 | |
| SCHEMBL9264064 | 0.81 | KEAP1 (0.46) | HTR6ALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL17119519 | 0.79 | KDM4E (0.43) | HTR6MTNR1AMTNR1BALDH1A1NQO2 | |
| SCHEMBL31121639 | 0.76 | HTR6 (0.56) | HTR6MTNR1AMTNR1BNQO2HTR7 | |
| SCHEMBL2338975 | 0.76 | HTR6 (0.56) | HTR6MTNR1AMTNR1BNQO2HTR7 | |
| SCHEMBL16339829 | 0.75 | HTR6 (0.40) | HTR6MTNR1AMTNR1BALDH1A1NQO2 | |
| SCHEMBL10860909 | 0.74 | MTNR1A (0.40) | HTR6MTNR1AMTNR1BALDH1A1NQO2 | |
| SCHEMBL5859128 | 0.73 | HTR6 (0.50) | HTR6MTNR1AMTNR1BNQO2KMT2A | |
| SCHEMBL8952468 | 0.73 | HTR6 (0.54) | HTR6MTNR1AMTNR1BNQO2HTR7 | |
| SCHEMBL11817887 | 0.73 | MAPT (0.51) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170172147-A1 | BIO-INSPIRED AND ANTIMICROBIAL POLYMERS CONTAINING AMINO ACID-LIKE MONOMER BUILDING BLOCKS | NATIONAL SCIENCE FOUNDATION | 2017-06-22 | — | — | US | disclosed |
| US-8093427-B2 | Construction and screening of solution-phase derived library of fenbufen and ethacrynic acid | NATIONAL TSING HUA UNIVERSITY (TW) | 2012-01-10 | — | — | US | disclosed |
| US-20110306668-A1 | CONSTRUCTION AND SCREENING OF SOLUTION-PHASE DERIVED LIBRARY OF FENBUFEN AND ETHACRYNIC ACID | NATIONAL TSING HUA UNIVERSITY (TW) | 2011-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170172147-A1 | BIO-INSPIRED AND ANTIMICROBIAL POLYMERS CONTAINING AMINO ACID-LIKE MONOMER BUILDING BLOCKS | PAM, ARG1, ASNS | HTR6 4419/4885DUSP10 3830/4885MTNR1A 4509/4885 |
| US-20110306668-A1 | CONSTRUCTION AND SCREENING OF SOLUTION-PHASE DERIVED LIBRARY OF FENBUFEN AND ETHACRYNIC ACID | CYP4F2, ACR, CYP4F3 | HTR6 741/4885DUSP10 3356/4885MTNR1A 2182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.