Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10863359 | 0.89 | ALDH1A1 (0.47) | MAPTLMNARAB9ACYP1A2CYP2C19 | |
| SCHEMBL10864256 | 0.81 | MAPT (0.47) | MAPTLMNAGLO1RAB9AALDH1A1 | |
| SCHEMBL9564468 | 0.79 | MAPT (0.45) | MAPTLMNAGLO1RAB9AALDH1A1 | |
| SCHEMBL10864550 | 0.79 | MAPT (0.45) | MAPTLMNAGLO1RAB9AALDH1A1 | |
| SCHEMBL9564466 | 0.79 | MAPT (0.45) | MAPTLMNAGLO1RAB9AALDH1A1 | |
| SCHEMBL10628854 | 0.78 | ALDH1A1 (0.50) | MAPTLMNACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL10628848 | 0.78 | ALDH1A1 (0.50) | MAPTLMNACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL7083137 | 0.77 | MAPT (0.36) | MAPTLMNAGLO1CYP1A2CYP2C19 | |
| SCHEMBL7083139 | 0.77 | MAPT (0.36) | MAPTLMNAGLO1CYP1A2CYP2C19 | |
| SCHEMBL1345391 | 0.77 | CYP2D6 (0.38) | MAPTLMNAGLO1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0168733-A2 | Process for the preparation of quinolinone and naphthyridoncarboxylic acids | BAYER AG (DE) | 1986-01-22 | — | — | EP | disclosed |