Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10863359 | 0.86 | ALDH1A1 (0.47) | MAPTLMNAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL10864550 | 0.83 | MAPT (0.45) | MAPTLMNAGLO1KMT2AALDH1A1 | |
| SCHEMBL10861885 | 0.81 | MAPT (0.47) | MAPTLMNAGLO1KMT2AALDH1A1 | |
| SCHEMBL10864814 | 0.81 | GLO1 (0.49) | MAPTLMNAGLO1KMT2AALDH1A1 | |
| SCHEMBL9564466 | 0.81 | MAPT (0.45) | MAPTLMNAGLO1KMT2AALDH1A1 | |
| SCHEMBL9564468 | 0.81 | MAPT (0.45) | MAPTLMNAGLO1KMT2AALDH1A1 | |
| SCHEMBL1005272 | 0.78 | MAPT (0.43) | MAPTLMNAGLO1KMT2AALDH1A1 | |
| SCHEMBL6482749 | 0.78 | MAPT (0.43) | MAPTLMNAGLO1KMT2AALDH1A1 | |
| SCHEMBL9149040 | 0.76 | MAPT (0.44) | MAPTLMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL9149036 | 0.76 | MAPT (0.44) | MAPTLMNAKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0168733-A2 | Process for the preparation of quinolinone and naphthyridoncarboxylic acids | BAYER AG (DE) | 1986-01-22 | — | — | EP | disclosed |