Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | DHODH | Q02127 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.36 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9306236 | 0.82 | KDM4E (0.43) | MAPTDHODHGAATDP1MEN1 | |
| SCHEMBL10375594 | 0.82 | USP2 (0.46) | MAPTDHODHGAATDP1MEN1 | |
| SCHEMBL10863678 | 0.81 | MEN1 (0.51) | MAPTDHODHGAATDP1MEN1 | |
| SCHEMBL10628848 | 0.81 | ALDH1A1 (0.50) | MAPTDHODHGAATDP1MEN1 | |
| SCHEMBL10628854 | 0.81 | ALDH1A1 (0.50) | MAPTDHODHGAATDP1MEN1 | |
| SCHEMBL10862684 | 0.81 | LMNA (0.46) | MAPTDHODHGAATDP1MEN1 | |
| SCHEMBL10863359 | 0.80 | ALDH1A1 (0.47) | MAPTDHODHGAATDP1KMT2A | |
| SCHEMBL10862944 | 0.78 | MEN1 (0.46) | MAPTDHODHGAATDP1MEN1 | |
| SCHEMBL4958597 | 0.77 | MAPT (0.44) | MAPTDHODHGAATDP1MEN1 | |
| SCHEMBL4958601 | 0.77 | MAPT (0.44) | MAPTDHODHGAATDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0168733-A2 | Process for the preparation of quinolinone and naphthyridoncarboxylic acids | BAYER AG (DE) | 1986-01-22 | — | — | EP | disclosed |