SCHEMBL1086283

SCHEMBL1086283

CCC(=O)N1CCN(CCC(CO)COC(c2ccccc2)(c2ccc(OC)cc2)c2ccc(OC)cc2)CC1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD3 P35462 3/20 0.51
SLC6A11 P48066 5/20 0.46
SLC6A1 P30531 2/20 0.46
SIGMAR1 Q99720 2/20 0.44
MEN1 O00255 1/20 0.42
TP53 P04637 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
KMT2A Q03164 1/20 0.42
SLC6A12 P48065 1/20 0.42
SLC6A13 Q9NSD5 1/20 0.42
CHRM3 P20309 1/20 0.41
DRD2 P14416 2/20 0.41
KCNA5 P22460 1/20 0.41
MAPK1 P28482 2/20 0.41
ALDH1A1 P00352 1/20 0.41
HTR1A P08908 1/20 0.40
CACNA1A O00555 1/20 0.40
CACNA2D1 P54289 1/20 0.40
CACNB1 Q02641 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1095780 0.89 SLC6A11 (0.46) DRD3SLC6A11SLC6A1SIGMAR1MEN1
SCHEMBL13770439 0.87 SLC6A11 (0.45) DRD3SLC6A11SLC6A1SIGMAR1MEN1
SCHEMBL1095803 0.86 SLC6A11 (0.44) DRD3SLC6A11SLC6A1SIGMAR1MEN1
SCHEMBL16214813 0.77 KIF11 (0.50) SLC6A11SLC6A1
SCHEMBL3487683 0.77 KIF11 (0.50) SLC6A11SLC6A1
SCHEMBL15730746 0.75 KIF11 (0.43) SLC6A11SLC6A1MEN1KMT2A
SCHEMBL24383387 0.72 SLC6A11 (0.45) SLC6A11SLC6A1MEN1TP53CYP1A2
SCHEMBL15709164 0.72 KIF11 (0.50) SLC6A11SLC6A1
SCHEMBL13881801 0.72 KIF11 (0.50) SLC6A11SLC6A1
SCHEMBL31711497 0.72 KMT2A (0.47) MEN1CYP1A2CYP3A4KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153827-B2 Reagents for biomolecular labeling, detection and quantification employing Raman spectroscopy PURDUE RESEARCH FOUNDATION (US) 2012-04-10 US disclosed
US-20090219526-A1 REAGENTS FOR BIOMOLECULAR LABELING, DETECTION AND QUANTIFICATION EMPLOYING RAMAN SPECTROSCOPY NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2009-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090219526-A1 REAGENTS FOR BIOMOLECULAR LABELING, DETECTION AND QUANTIFICATION EMPLOYING RAMAN SPECTROSCOPY SRMS, UQCRB, UQCRC1 DRD3 2117/4885SLC6A11 4474/4885SLC6A1 4553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.