Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10869100 | 0.82 | ALDH1A1 (0.51) | ALDH1A1ATML3MBTL1RAB9ANPC1 | |
| SCHEMBL10717874 | 0.81 | ALDH1A1 (0.47) | ALDH1A1ATML3MBTL1RAB9ANPC1 | |
| SCHEMBL13860334 | 0.75 | ALDH1A1 (0.42) | ALDH1A1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL9596037 | 0.75 | ALDH1A1 (0.41) | ALDH1A1ATML3MBTL1RAB9ANPC1 | |
| SCHEMBL10716456 | 0.73 | PKM (0.49) | ALDH1A1ATML3MBTL1RAB9ANPC1 | |
| SCHEMBL28966164 | 0.71 | RAB9A (0.67) | ALDH1A1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL29872446 | 0.71 | RAB9A (0.67) | ALDH1A1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL10718989 | 0.70 | PKM (0.49) | ALDH1A1ATML3MBTL1RAB9ANPC1 | |
| SCHEMBL10717754 | 0.70 | ALDH1A1 (0.52) | ALDH1A1ATML3MBTL1RAB9ANPC1 | |
| SCHEMBL24320358 | 0.68 | RAB9A (0.56) | ALDH1A1RAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174832-A2 | Ethene derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |