SCHEMBL10864014

SCHEMBL10864014

CCO[Si](CCCN(C)C(=O)NC)(OCC)OCC

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16310806 0.83
SCHEMBL3341522 0.81 BCHE (0.31) EPHX2
SCHEMBL3212658 0.81 CHRM1 (0.31)
SCHEMBL3207871 0.81 EPHX2 (0.30) EPHX2
SCHEMBL16079779 0.81 EPHX2 (0.46) EPHX2
SCHEMBL4417326 0.80 EPHX2 (0.38) EPHX2
SCHEMBL10863727 0.79 ALOX15 (0.30)
SCHEMBL17133203 0.78
SCHEMBL128324 0.78 CA12 (0.33)
SCHEMBL17133215 0.76 KEAP1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4623740-A N,N'- and N,N',N'-substituted silylureas and process for their production DEGUSSA AKTIENGESELLSCHAFT (DE) 1986-11-18 US disclosed
EP-0169992-A1 N,N'- and N,N',N'-substituted silylureas and process for their preparation Degussa Aktiengesellschaft (DE) 1986-02-05 EP disclosed