SCHEMBL16079779

SCHEMBL16079779

CCO[Si](CCCNC(=O)N(C)CCCCCCN(C)C(=O)NCCC[Si](OCC)(OCC)OCC)(OCC)OCC

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.46
DNM1 Q05193 2/20 0.33
LMNA P02545 1/20 0.32
EPHX1 P07099 3/20 0.32
ACHE P22303 5/20 0.31
BCHE P06276 1/20 0.31
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4417326 0.90 EPHX2 (0.38) EPHX2
SCHEMBL10864611 0.83 CHRNB2 (0.41) DNM1EPHX1ACHECA12CA1
SCHEMBL1203085 0.82 EPHX1 (0.40) EPHX2DNM1EPHX1
SCHEMBL29837984 0.82 EPHX1 (0.40) EPHX2DNM1EPHX1
SCHEMBL13934745 0.82 EPHX1 (0.40) EPHX2DNM1EPHX1
SCHEMBL10864014 0.81 EPHX2 (0.31) EPHX2
SCHEMBL2563904 0.81 CA12 (0.32) EPHX1ACHECA12CA1CA2
SCHEMBL2616684 0.79 ACHE (0.33) DNM1EPHX1ACHECA12CA1
SCHEMBL4407700 0.79 EPHX1 (0.36) EPHX2EPHX1CA12CA1CA2
SCHEMBL5916615 0.79 BCHE (0.35) EPHX2LMNAACHEBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3585845-B1 SILOXANE-BASED COATINGS CONTAINING POLYMERS WITH UREA LINKAGES AND TERMINAL ALKOXYSILANES US GOV SEC NAVY (US) 2024-11-20 EP disclosed
US-9139753-B2 Single-component moisture-curable coatings based on N-substituted urea polymers with extended chains and terminal alkoxysilanes THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2015-09-22 US disclosed
US-20140275405-A1 SINGLE-COMPONENT MOISTURE-CURABLE COATINGS BASED ON N-SUBSTITUTED UREA POLYMERS WITH EXTENDED CHAINS AND TERMINAL ALKOXYSILANES THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE NAVY 2014-09-18 US disclosed