Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 17/20 | 0.55 |
| ▸ | HTR1A | P08908 | 9/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10503675 | 0.87 | ADRB2 (0.58) | ADRB2HTR1AALDH1A1ADRB1LMNA | |
| SCHEMBL10503979 | 0.84 | ADRB2 (0.52) | ADRB2HTR1AALDH1A1ADRB1LMNA | |
| SCHEMBL10505297 | 0.83 | ADRB1 (0.59) | ADRB2ADRB1ADRB3CYP1A2KDM4E | |
| SCHEMBL10865572 | 0.82 | ADRB2 (0.55) | ADRB2HTR1AALDH1A1ADRB1LMNA | |
| SCHEMBL10505526 | 0.81 | HTR1A (0.46) | ADRB2HTR1AADRB1ADRB3SLC6A2 | |
| SCHEMBL10592520 | 0.80 | ADRB2 (0.52) | ADRB2HTR1AALDH1A1ADRB1LMNA | |
| SCHEMBL10503080 | 0.80 | ADRB2 (0.57) | ADRB2HTR1AALDH1A1ADRB1LMNA | |
| SCHEMBL10504871 | 0.79 | ADRB3 (0.49) | ADRB2HTR1AALDH1A1ADRB1LMNA | |
| SCHEMBL10503373 | 0.79 | ADRB2 (0.49) | ADRB2HTR1AALDH1A1ADRB1LMNA | |
| SCHEMBL10503528 | 0.78 | ADRB2 (0.47) | ADRB2HTR1AADRB1LMNASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200915-A1 | Aminopropanol derivatives, process for their preparation, their use and medicines containing them | Roche Diagnostics GmbH (DE) | 1986-11-12 | — | — | EP | disclosed |