Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 7/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21827124 | 0.86 | MAPK1 (0.67) | MAPK1CYP1A2CYP2D6L3MBTL1CYP3A4 | |
| SCHEMBL20469444 | 0.83 | ELANE (0.59) | MAPK1CYP1A2CYP2D6L3MBTL1CYP3A4 | |
| SCHEMBL21827055 | 0.81 | MEN1 (0.55) | MAPK1CYP1A2CYP2D6CYP3A4CYP2C19 | |
| SCHEMBL9357216 | 0.79 | RAB9A (0.65) | MAPK1CYP1A2CYP2D6L3MBTL1CYP3A4 | |
| SCHEMBL21767165 | 0.79 | CYP1A2 (0.46) | MAPK1CYP1A2CYP2D6L3MBTL1CYP3A4 | |
| SCHEMBL141138 | 0.78 | ALDH1A1 (0.70) | MAPK1CYP1A2CYP2D6L3MBTL1CYP3A4 | |
| SCHEMBL9357732 | 0.77 | RAB9A (0.63) | MAPK1CYP1A2CYP2D6L3MBTL1CYP3A4 | |
| SCHEMBL3077568 | 0.75 | CYP1A2 (0.69) | MAPK1CYP1A2CYP2D6L3MBTL1CYP3A4 | |
| SCHEMBL21886075 | 0.75 | LMNA (0.49) | MAPK1CYP1A2CYP2D6L3MBTL1CYP3A4 | |
| SCHEMBL774785 | 0.75 | CYP1A2 (0.73) | MAPK1CYP1A2CYP2D6L3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230165854-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH APJ RECEPTOR ACTIVITY | SHOUTI INC. | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230165854-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH APJ RECEPTOR ACTIVITY | APLNR, AGTR1, AGTR2 | MAPK1 1659/4885CYP1A2 2827/4885CYP2D6 2016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.