Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 4/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10867747 | 0.89 | MPO (0.53) | SLC6A4SLC6A2SLC6A3HTR1AMPO | |
| SCHEMBL10867330 | 0.89 | MTNR1A (0.45) | HTR1AMTNR1AMTNR1BHTR1DHTR1B | |
| SCHEMBL10868220 | 0.89 | HTR2A (0.56) | SLC6A4SLC6A2SLC6A3HTR1AMTNR1A | |
| Hydrochloric Acid SCHEMBL10867337 | 0.86 | SMN1; SMN2 (0.47) | SLC6A4HTR1AHTR2A | |
| SCHEMBL10868177 | 0.82 | HTR2A (0.52) | SLC6A4HTR1AHTR2A | |
| SCHEMBL10866980 | 0.80 | HTR2A (0.34) | HTR1AHTR2A | |
| SCHEMBL10868207 | 0.80 | MPO (0.54) | SLC6A4SLC6A2SLC6A3HTR1AMTNR1A | |
| SCHEMBL10866988 | 0.80 | HTR2A (0.59) | SLC6A4SLC6A2SLC6A3HTR1AMTNR1A | |
| SCHEMBL10868996 | 0.80 | MTNR1A (0.49) | HTR1AMTNR1AMTNR1BHTR1DHTR1B | |
| SCHEMBL10871125 | 0.78 | SMN1; SMN2 (0.51) | HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187122-A2 | 1,3,4-Trisubstituted azacycloalkanes or azacycloalkenes | CIBA-GEIGY AG (CH) | 1986-07-09 | — | — | EP | claimed |