Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 3/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 4/20 | 0.47 |
| ▸ | TACR2 | P21452 | 2/20 | 0.46 |
| ▸ | GLP1R | P43220 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10868207 | 0.91 | MPO (0.54) | MPOSLC6A4SLC6A2SLC6A3HTR1A | |
| SCHEMBL10867330 | 0.89 | MTNR1A (0.45) | HTR1AKCNH2 | |
| SCHEMBL10866637 | 0.89 | SLC6A4 (0.49) | MPOSLC6A4SLC6A2SLC6A3HTR1A | |
| SCHEMBL10868220 | 0.89 | HTR2A (0.56) | MPOSLC6A4SLC6A2SLC6A3HTR1A | |
| Hydrochloric Acid SCHEMBL10867337 | 0.86 | SMN1; SMN2 (0.47) | SLC6A4HTR1AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL10868177 | 0.82 | HTR2A (0.52) | SLC6A4HTR1AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL10866980 | 0.80 | HTR2A (0.34) | HTR1ACYP3A4KCNH2 | |
| SCHEMBL10866988 | 0.80 | HTR2A (0.59) | MPOSLC6A4SLC6A2SLC6A3HTR1A | |
| SCHEMBL10868996 | 0.80 | MTNR1A (0.49) | HTR1AKCNH2 | |
| SCHEMBL10871125 | 0.78 | SMN1; SMN2 (0.51) | HTR1AMEN1ALDH1A1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187122-A2 | 1,3,4-Trisubstituted azacycloalkanes or azacycloalkenes | CIBA-GEIGY AG (CH) | 1986-07-09 | — | — | EP | claimed |