Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 4/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 5/20 | 0.49 |
| ▸ | HTR7 | P34969 | 3/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | SPR | P35270 | 1/20 | 0.48 |
| ▸ | TACR2 | P21452 | 1/20 | 0.47 |
| ▸ | GLP1R | P43220 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10867747 | 0.91 | MPO (0.53) | MPOSLC6A4SLC6A2SLC6A3HTR1A | |
| SCHEMBL10866988 | 0.89 | HTR2A (0.59) | MPOSLC6A4SLC6A2SLC6A3NOTUM | |
| SCHEMBL10868996 | 0.89 | MTNR1A (0.49) | MTNR1AMTNR1BHTR1AKCNH2 | |
| SCHEMBL10871232 | 0.87 | HTR2A (0.50) | SLC6A4HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL10867806 | 0.86 | HTR2A (0.49) | SLC6A4HTR1AHTR7 | |
| Dimethylformamide SCHEMBL10866686 | 0.84 | MTNR1A (0.44) | SLC6A4MTNR1AMTNR1BHTR1AKCNH2 | |
| SCHEMBL10867065 | 0.81 | HTR1A (0.54) | SLC6A4HTR1AHTR7 | |
| SCHEMBL10868220 | 0.81 | HTR2A (0.56) | MPOSLC6A4SLC6A2SLC6A3NOTUM | |
| Hydrochloric Acid SCHEMBL10867944 | 0.80 | HTR1A (0.53) | SLC6A4HTR1AHTR7KCNH2 | |
| SCHEMBL10866637 | 0.80 | SLC6A4 (0.49) | MPOSLC6A4SLC6A2SLC6A3MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187122-A2 | 1,3,4-Trisubstituted azacycloalkanes or azacycloalkenes | CIBA-GEIGY AG (CH) | 1986-07-09 | — | — | EP | claimed |