SCHEMBL108687

SCHEMBL108687

C(=C/c1ccccc1)\CCc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GPR52 Q9Y2T5 2/20 0.48
SIGMAR1 Q99720 2/20 0.47
IDO1 P14902 2/20 0.47
PAM P19021 1/20 0.47
AKR1B10 O60218 1/20 0.44
AKR1B1 P15121 1/20 0.44
MMP1 P03956 1/20 0.44
POLB P06746 1/20 0.44
MMP2 P08253 1/20 0.44
MMP9 P14780 1/20 0.44
RECQL P46063 1/20 0.44
GRIN1 Q05586 1/20 0.44
GRIN2B Q13224 1/20 0.44
MAOB P27338 1/20 0.44
HTR2A P28223 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL108688 1.00 GPR52 (0.48) GPR52SIGMAR1IDO1PAMAKR1B10
SCHEMBL30742787 1.00 GPR52 (0.48) GPR52SIGMAR1IDO1PAMAKR1B10
SCHEMBL29841331 0.87 NAMPT (0.52) SIGMAR1IDO1PAMGRIN1GRIN2B
SCHEMBL4613657 0.87 NAMPT (0.52) SIGMAR1IDO1PAMGRIN1GRIN2B
SCHEMBL4613662 0.87 NAMPT (0.52) SIGMAR1IDO1PAMGRIN1GRIN2B
SCHEMBL31197196 0.86 GPR52 (0.55) GPR52SIGMAR1
SCHEMBL9271038 0.86 ALDH1A1 (0.46) GPR52PAM
SCHEMBL154597 0.86 TAAR1 (0.53) GPR52AKR1B10AKR1B1MMP1MMP2
SCHEMBL9271024 0.86 ALDH1A1 (0.46) GPR52PAM
SCHEMBL31197204 0.86 NFE2L2 (0.55) GPR52SIGMAR1GRIN1GRIN2BMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2463374-A2 Isolated alcohol dehydrogenase enzymes and uses thereof Bio Architecture Lab, Inc. (US) 2012-06-13 EP claimed
US-20090155873-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-18 US claimed
US-20090139134-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-04 US claimed
EP-3230463-B2 RAPID PRETREATMENT APALTA PATENTS OUE (EE) 2025-07-16 EP disclosed
US-20240425893-A1 RAPID PRETREATMENT Apalta Patents OÜ (EE) 2024-12-26 US disclosed
US-12054761-B2 Rapid pretreatment Apalta Patents OÜ (EE) 2024-08-06 US disclosed
US-11821047-B2 High pressure zone formation for pretreatment Apalta Patent OÜ (EE) 2023-11-21 US disclosed
CN-116462665-B Organic light-emitting material and organic electroluminescent device 季华实验室 2023-10-10 CN disclosed
US-20230295678-A1 RAPID PRETREATMENT Apalta Patents OÜ (EE) 2023-09-21 US disclosed
CN-116514778-A Organic electronic transmission material and organic electroluminescent device 季华实验室 2023-08-01 CN disclosed
CN-116462665-A Organic light-emitting material and organic electroluminescent device 季华实验室 2023-07-21 CN disclosed
US-20090139134-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-04 US disclosed
WO-2008127291-A2 ADVANCED DRUG DEVELOPMENT AND MANUFACTURING LOS ALAMOS NATIONAL SECURITY, LLC (US) 2008-10-23 WO disclosed
US-20080220441-A1 Advanced drug development and manufacturing THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2008-09-11 US disclosed
US-6329546-B1 FOR INVESTIGATING THE MECHANISM OF ACTION OF A PHYSIOLOGICALLY ACTIVE AMINO ACID COMPOUND SUCH AS GLUTAMIC ACID IN AN ORGANISM LABORATORY OF MOLECULAR BIOPHOTONICS (JP) 2001-12-11 US disclosed
US-6229020-B1 REACTING N-SUCCINIMIDYL AND P-NITROPHENYL CINNAMATE DERIVATIVES WITH PHYSIOLOGICALLY ACTIVE SUBSTANCE SUCH AS AN AMINO ACID; PROTECTING AMINO OR HYDROXY GROUPS FOR ANALYSIS OF BIOLOGICAL REACTIONS BY IRRADIATION WITH LIGHT LABORATORY OF MOLECULAR BIOPHOTONICS (JP) 2001-05-08 US disclosed
WO-1999026885-A1 COMPOSITIONS AND METHODS FOR ADSORPTION AND REMEDIATION OF ORGANIC COMPOUNDS UNIVERSITY OF FLORIDA (US) 1999-06-03 WO disclosed
EP-0180771-B1 METHOD FOR IMPROVING IMPULSE BREAKDOWN STRENGTH OF ELECTRICALLY INSULATING MATERIALS Nippon Petrochemicals Co., Ltd. (JP) 1989-08-02 EP disclosed
US-4845201-A Process for producing organolanthanides, the resultant compounds and their use INSTITUT FRANCAIS DU PETROLE (FR) 1989-07-04 US disclosed
US-3932423-A TREATMENT OF PSYCHOLOGICAL DISORDERS YOSHITOMI PHARMACEUTICAL INDUSTRIES (JA) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090139134-A1 BIOFUEL PRODUCTION MGAM, DCXR, MANBA GPR52 1379/4885SIGMAR1 4688/4885IDO1 2541/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.