SCHEMBL108688

SCHEMBL108688

C(=Cc1ccccc1)CCc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GPR52 Q9Y2T5 2/20 0.48
SIGMAR1 Q99720 2/20 0.47
IDO1 P14902 2/20 0.47
PAM P19021 1/20 0.47
AKR1B10 O60218 1/20 0.44
AKR1B1 P15121 1/20 0.44
MMP1 P03956 1/20 0.44
POLB P06746 1/20 0.44
MMP2 P08253 1/20 0.44
MMP9 P14780 1/20 0.44
RECQL P46063 1/20 0.44
GRIN1 Q05586 1/20 0.44
GRIN2B Q13224 1/20 0.44
MAOB P27338 1/20 0.44
HTR2A P28223 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL108687 1.00 GPR52 (0.48) GPR52SIGMAR1IDO1PAMAKR1B10
SCHEMBL30742787 1.00 GPR52 (0.48) GPR52SIGMAR1IDO1PAMAKR1B10
SCHEMBL29841331 0.87 NAMPT (0.52) SIGMAR1IDO1PAMGRIN1GRIN2B
SCHEMBL4613657 0.87 NAMPT (0.52) SIGMAR1IDO1PAMGRIN1GRIN2B
SCHEMBL4613662 0.87 NAMPT (0.52) SIGMAR1IDO1PAMGRIN1GRIN2B
SCHEMBL31197196 0.86 GPR52 (0.55) GPR52SIGMAR1
SCHEMBL9271038 0.86 ALDH1A1 (0.46) GPR52PAM
SCHEMBL154597 0.86 TAAR1 (0.53) GPR52AKR1B10AKR1B1MMP1MMP2
SCHEMBL9271024 0.86 ALDH1A1 (0.46) GPR52PAM
SCHEMBL31197204 0.86 NFE2L2 (0.55) GPR52SIGMAR1GRIN1GRIN2BMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106699971-A Environment-friendly carboxylic butadiene-styrene latex for papermaking and preparation method thereof 杭州蓝诚新材料有限公司 2017-05-24 CN claimed
CN-102115354-B Allylation method of aromatic hydrocarbon UNIV CHONGQING 2013-06-19 CN claimed
EP-2463374-A2 Isolated alcohol dehydrogenase enzymes and uses thereof Bio Architecture Lab, Inc. (US) 2012-06-13 EP claimed
CN-102115354-A Allylation method of aromatic hydrocarbon UNIV CHONGQING 2011-07-06 CN claimed
US-20090155873-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-18 US claimed
US-20090139134-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-04 US claimed
EP-0831167-A2 Use of aryloxy polyglykolethers as levelling and dispersing agent Clariant GmbH (DE) 1998-03-25 EP claimed
EP-3230463-B2 RAPID PRETREATMENT APALTA PATENTS OUE (EE) 2025-07-16 EP disclosed
CN-111936457-B Enol ether pro-fragrances 弗门尼舍有限公司 2025-02-25 CN disclosed
US-20240425893-A1 RAPID PRETREATMENT Apalta Patents OÜ (EE) 2024-12-26 US disclosed
CN-117482924-B Preparation and application of propane diamine modified column arene multifunctional chromatographic packing 兰州城市学院 2024-11-29 CN disclosed
CN-117482924-B Preparation and application of propane diamine modified column arene multifunctional chromatographic packing 兰州城市学院 2024-11-29 CN disclosed
US-12054761-B2 Rapid pretreatment Apalta Patents OÜ (EE) 2024-08-06 US disclosed
US-4506107-A CAPACITORS, CABLES, TRANSFORMERS, PLASTICS NIPPON PETROCHEMICAL COMPANY, LIMITED (JP) 1985-03-19 US disclosed
US-4493943-A MIXTURES OF DIARYLALKANES AND AROMATIC MONO-OR DI-OLEFINS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1985-01-15 US disclosed
EP-0103868-A2 Improved electrical insulating oil and oil-filled electrical appliances NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1984-03-28 EP disclosed
US-4378984-A Distillative freezing process for separating volatile mixtures CHENG CHEN YEN 1983-04-05 US disclosed
US-4218893-A Distillative freezing process for separating volatile mixtures and apparatuses for use therein SING-WANG CHENG FAMILY LIMITED PARTNERSHIP 1980-08-26 US disclosed
US-4049736-A SILICA GEL CATALYST THE DOW CHEMICAL COMPANY (US) 1977-09-20 US disclosed
US-3946081-A OXIDATION CATALYSTS, GROUP V, VI, OR VII OXIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090139134-A1 BIOFUEL PRODUCTION MGAM, DCXR, MANBA GPR52 1379/4885SIGMAR1 4688/4885IDO1 2541/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.