SCHEMBL10869147

SCHEMBL10869147

N=C(N)N(c1cccc(C(F)(F)F)c1)[N+](=O)[O-]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.41
FBP1 P09467 1/20 0.41
SRD5A2 P31213 1/20 0.39
KIF11 P52732 2/20 0.39
HTR3E A5X5Y0 1/20 0.39
HTR3B O95264 1/20 0.39
HTR3A P46098 1/20 0.39
HTR3D Q70Z44 1/20 0.39
HTR3C Q8WXA8 1/20 0.39
ALDH1A1 P00352 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
AKR1B1 P15121 1/20 0.38
AKR1C4 P17516 1/20 0.38
AKR1C3 P42330 1/20 0.38
AKR1C2 P52895 1/20 0.38
AKR1C1 Q04828 1/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
PRSS1 P07477 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27920579 0.78 PRSS1 (0.58) CES2ALDH1A1MEN1KMT2ATSHR
SCHEMBL27723651 0.77 FBP1 (0.49) CES2FBP1KIF11ALDH1A1MEN1
SCHEMBL3389830 0.77 HTR3E (0.46) CES2KIF11HTR3EHTR3BHTR3A
SCHEMBL4384248 0.76 ALDH1A1 (0.40) FBP1ALDH1A1MEN1KMT2AMAPK1
Hydrochloric Acid SCHEMBL15527206 0.75 KMT2A (0.39) FBP1ALDH1A1MEN1KMT2APRSS1
SCHEMBL11578705 0.75 CES2 (0.45) CES2KIF11HTR3EHTR3BHTR3A
Benzoic Acid SCHEMBL8013438 0.73 TSHR (0.45) CES2SRD5A2MEN1KMT2ATSHR
SCHEMBL10384411 0.72 ALDH1A1 (0.45) ALDH1A1MEN1KMT2AAKR1C4AKR1C3
Nitric Acid SCHEMBL28200782 0.71 FBP1 (0.53) CES2FBP1KIF11HTR3EHTR3B
SCHEMBL5606524 0.70 CES2 (0.50) CES2SRD5A2KIF11HTR3EHTR3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0189579-A1 Substituted nitro and cyanoguanidines and their use for increasing crop yield AMERICAN CYANAMID COMPANY (US) 1986-08-06 EP claimed
EP-0113070-A1 The use of substituted nitro and cyanoguanidines for increasing crop yield AMERICAN CYANAMID COMPANY (US) 1984-07-11 EP claimed