Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.43 |
| ▸ | CA2 | P00918 | 7/20 | 0.43 |
| ▸ | CA5A | P35218 | 7/20 | 0.43 |
| ▸ | CA7 | P43166 | 7/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 7/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1874184 | 0.84 | CYP2C9 (0.42) | CA1CA2CA5ACA7CA5B | |
| SCHEMBL5064646 | 0.74 | GABRA1 (0.59) | CA1CA2CA5ACA7CA5B | |
| SCHEMBL10638501 | 0.74 | CDK2 (0.48) | CA1CA2CA5ACA7CA5B | |
| SCHEMBL11823652 | 0.72 | HSPA5 (0.58) | CYP2C9KMT2AL3MBTL1POLBNPC1 | |
| SCHEMBL1500502 | 0.72 | MMP1 (0.42) | CA1CA2CA12CA9CDK2 | |
| SCHEMBL5679972 | 0.70 | CISD1 (0.37) | CA1CA2CA5ACA7CA5B | |
| SCHEMBL5999818 | 0.70 | CYP2C9 (0.54) | CA1CA2CA7CA12CA9 | |
| SCHEMBL30505689 | 0.69 | CYP2C9 (0.50) | CYP2C9KMT2AMEN1POLBNPC1 | |
| SCHEMBL7001903 | 0.69 | NPC1 (0.54) | CYP2C9KMT2AL3MBTL1POLBNPC1 | |
| SCHEMBL5518503 | 0.67 | CDK2 (0.63) | CA1CA2CA5ACA7CA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187470-A2 | Herbicidal heteroarylbenzene sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-07-16 | — | — | EP | disclosed |