Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10371339 | 0.79 | ROCK2 (0.32) | CHRM2MEN1CYP2D6KMT2ACHRM1 | |
| SCHEMBL11093215 | 0.78 | ALDH1A1 (0.33) | CHRM2MEN1CYP2D6KMT2ACHRM1 | |
| SCHEMBL10369482 | 0.78 | ADAM17 (0.31) | CHRM2MEN1CYP2D6KMT2ACHRM1 | |
| SCHEMBL27796315 | 0.75 | ACE (0.35) | — | |
| SCHEMBL10869319 | 0.74 | GAA (0.44) | MEN1KMT2A | |
| SCHEMBL23131022 | 0.74 | ENO1 (0.32) | — | |
| SCHEMBL5968406 | 0.73 | NPC1 (0.33) | MEN1KMT2A | |
| SCHEMBL10870110 | 0.73 | ACE (0.39) | — | |
| SCHEMBL28915886 | 0.71 | ELANE (0.32) | ELANE | |
| SCHEMBL10368380 | 0.69 | ALDH1A1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0184861-A1 | Derivatives of the 3-mercapto-2-oxo-1-pyrrolidinacetic acid, process for their preparation and pharmaceutical compositions containing them | PROTER S.p.A. (IT) | 1986-06-18 | — | — | EP | disclosed |