SCHEMBL5652323

SCHEMBL5652323

CC(=O)OCCNC=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6320569 0.87 ALDH1A1 (0.50)
SCHEMBL19384420 0.81 ADH1B (0.40)
SCHEMBL68618 0.80 ALDH1A1 (0.50)
SCHEMBL18611042 0.80 ADH1B (0.41)
SCHEMBL19263632 0.80
SCHEMBL1086964 0.79 THRB (0.48)
SCHEMBL19384422 0.79
SCHEMBL18265593 0.78 NAAA (0.45)
SCHEMBL8955075 0.78 ADH1B (0.39)
Hydrochloric Acid SCHEMBL1062025 0.78 ALDH1A1 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5059713-A Selective catalytic cracking of carboxylic acid amides with magnesium sulfide and mixed oxides catalyst AIR PRODUCTS AND CHEMICALS, INC. (US) 1991-10-22 US claimed
CN-120020116-A Process for the preparation of N-alkenylamides 中国石油化工股份有限公司 2025-05-20 CN disclosed
CN-120020119-A Process for preparing N- (2-substituted ethyl) amides and N-vinyl amides 中国石油化工股份有限公司 2025-05-20 CN disclosed
CN-120020120-A Method for producing N- (2-acyloxyalkyl) amides and use thereof 中国石油化工股份有限公司 2025-05-20 CN disclosed
CN-114075237-B Preparation method of titanium diol 中国石油化工股份有限公司 2024-01-19 CN disclosed
CN-114075237-A Preparation method of titanium dialkoxide 中国石油化工股份有限公司 2022-02-22 CN disclosed
EP-3034510-A1 OLIGONUCLEOTIDES COMPRISING A C5-MODIFIED PYRIMIDINE Alnylam Pharmaceuticals Inc. (US) 2016-06-22 EP disclosed
CN-104327006-A Preparation method of 5-ehtyl-4-formamidooxazole Hunan huateng pharmaceutical co ltd 2015-02-04 CN disclosed
EP-1725548-B1 PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF ASPARTIC ACETAL CASPASE INHIBITORS VERTEX PHARMA (US) 2015-01-14 EP disclosed
EP-2399916-B1 Process and intermediates for the preparation of aspartic acetal caspase ihnhibitors VERTEX PHARMA (US) 2014-12-10 EP disclosed
US-20110178069-A1 INHIBITORS OF INTERLEUKIN-1 BETA CONVERTING ENZYME VERTEX PHARMACEUTICALS INCORPORATED (US) 2011-07-21 US disclosed
US-20070049620-A1 Cyclic tertiary amine compound SANKYO COMPANY, LIMITED (JP) 2007-03-01 US disclosed
EP-1632488-A1 CYCLIC TERTIARY AMINE COMPOUND Sankyo Company, Limited (JP) 2006-03-08 EP disclosed
EP-0863881-A1 BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1998-09-16 EP disclosed
WO-1997010219-A1 BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-03-20 WO disclosed
US-5059713-A Selective catalytic cracking of carboxylic acid amides with magnesium sulfide and mixed oxides catalyst AIR PRODUCTS AND CHEMICALS, INC. (US) 1991-10-22 US disclosed
EP-0001333-B1 CLAVULANIC ACID DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM BEECHAM GROUP PLC (GB) 1982-09-15 EP disclosed
US-4203898-A ANTICARCINOGENIC ELI LILLY AND COMPANY (US) 1980-05-20 US disclosed
EP-0008899-A1 Clavulanic acid derivatives, their preparation and pharmaceutical compositions containing them BEECHAM GROUP PLC (GB) 1980-03-19 EP disclosed
EP-0001333-A1 Clavulanic acid derivatives, their preparation and pharmaceutical compositions containing them BEECHAM GROUP PLC (GB) 1979-04-04 EP disclosed