SCHEMBL10869801

SCHEMBL10869801

CN(C)CCN1CCC(O)CC1

nearest known ligand 0.52

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 2/20 0.41
SPHK1 Q9NYA1 1/20 0.40
ALOX15 P16050 1/20 0.37
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 1/20 0.34
GAA P10253 1/20 0.34
SLC6A5 Q9Y345 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15473888 0.88 HRH3 (0.37) KCNA3HRH3
SCHEMBL10867123 0.88 HRH3 (0.37) KCNA3HRH3
SCHEMBL15473856 0.88 HRH3 (0.37) KCNA3HRH3
SCHEMBL27104567 0.88 ALOX15 (0.49) KCNA3SPHK1ALOX15SLC6A5HRH3
SCHEMBL24906776 0.83 KCNA3 (0.39) KCNA3SPHK1KDM4EALDH1A1GAA
SCHEMBL15471218 0.80 KDM4E (0.37) KCNA3SPHK1ALOX15KDM4EALDH1A1
SCHEMBL14174957 0.80 CARM1 (0.52) HRH3
SCHEMBL21430360 0.78 ALOX15 (0.37) ALOX15KDM4EALDH1A1SLC6A5HRH3
SCHEMBL18173275 0.78 ALOX15 (0.37) ALOX15KDM4EALDH1A1SLC6A5HRH3
SCHEMBL6945949 0.78 GNAI3 (0.50) SPHK1ALOX15SLC6A5HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0178946-A2 1-(Aminoalkyl)-alpha, alpha-diaryl pyrrolidine-piperidine- and homopiperidine- acetamides and acetonitriles A.H. ROBINS COMPANY, INCORPORATED (US) 1986-04-23 EP claimed
US-20260102348-A1 COMPOUND OR SALT THEREOF AND LIPID PARTICLES FUJIFILM CORPORATION (JP) 2026-04-16 US disclosed
US-12508226-B2 Lipid composition FUJIFILM CORPORATION (JP) 2025-12-30 US disclosed
US-12370143-B2 Compound or salt thereof and lipid particles FUJIFILM CORPORATION (JP) 2025-07-29 US disclosed
EP-4328309-B1 LIPID COMPOSITION FUJIFILM CORP (JP) 2025-07-02 EP disclosed
US-12285525-B2 Compound or salt thereof and lipid particles FUJIFILM CORPORATION (JP) 2025-04-29 US disclosed
CN-116172975-B Lipid particle, nucleic acid drug comprising same, and composition for nucleic acid delivery 富士胶片株式会社 2025-03-28 CN disclosed
CN-114728016-B Lipid composition 富士胶片株式会社 2024-10-29 CN disclosed
US-20240315970-A1 COMPOUND OR SALT THEREOF AND LIPID PARTICLES FUJIFILM CORPORATION (JP) 2024-09-26 US disclosed
CN-113924128-B Lipid composition 富士胶片株式会社 2024-09-06 CN disclosed
EP-3805198-A1 COMPOUND, SALT THEREOF AND LIPID PARTICLES FUJIFILM Corporation (JP) 2021-04-14 EP disclosed
US-20210085604-A1 COMPOUND OR SALT THEREOF AND LIPID PARTICLES FUJIFILM CORPORATION (JP) 2021-03-25 US disclosed
US-20210085604-A1 COMPOUND OR SALT THEREOF AND LIPID PARTICLES FUJIFILM CORPORATION (JP) 2021-03-25 US disclosed
CN-112262122-A Compound or salt thereof, and lipid particle 富士胶片株式会社 2021-01-22 CN disclosed
US-9139609-B2 C-4″ position substituted macrolide derivative TAISHO PHARMACEUTICAL CO., LTD. (JP) 2015-09-22 US disclosed
EP-2206707-B1 AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF ASTELLAS PHARMA INC (JP) 2014-07-23 EP disclosed
US-20140046043-A1 C-4\" POSITION SUBSTITUTED MACROLIDE DERIVATIVE MEIJI SEIKA PHARMA CO., LTD. (JP) 2014-02-13 US disclosed
US-8304547-B2 Azolecarboxamide compound or salt thereof ASTELLAS PHARMA INC. (JP) 2012-11-06 US disclosed
US-8304547-B2 Azolecarboxamide compound or salt thereof ASTELLAS PHARMA INC. (JP) 2012-11-06 US disclosed
US-20100249088-A1 AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF ASTELLAS PHARMA INC. (JP) 2010-09-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12370143-B2 Compound or salt thereof and lipid particles NR1H3, NR1H2, LDLR KCNA3 4050/4885SPHK1 1166/4885ALOX15 1103/4885
US-12285525-B2 Compound or salt thereof and lipid particles NR1H3, NR1H2, LDLR KCNA3 4050/4885SPHK1 1166/4885ALOX15 1103/4885
US-20240315970-A1 COMPOUND OR SALT THEREOF AND LIPID PARTICLES NR1H3, NR1H2, LDLR KCNA3 4050/4885SPHK1 1166/4885ALOX15 1103/4885
US-20260102348-A1 COMPOUND OR SALT THEREOF AND LIPID PARTICLES LDLR, NR1H3, NR1H2 KCNA3 4603/4885SPHK1 1371/4885ALOX15 611/4885
US-20210085604-A1 COMPOUND OR SALT THEREOF AND LIPID PARTICLES NR1H3, NR1H2, LDLR KCNA3 4071/4885SPHK1 1171/4885ALOX15 1156/4885
US-20140046043-A1 C-4\" POSITION SUBSTITUTED MACROLIDE DERIVATIVE MRPL21, MRPS34, MRPL37 KCNA3 1772/4885SPHK1 3613/4885ALOX15 4684/4885
US-20100249088-A1 AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF TRPV1, FGFR3, GPR17 KCNA3 1452/4885SPHK1 1973/4885ALOX15 2657/4885
US-12508226-B2 Lipid composition APOB, NAF1, SLC27A1 KCNA3 4143/4885SPHK1 1190/4885ALOX15 519/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.