Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.45 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10870623 | 0.87 | HDAC1 (0.48) | HDAC1HDAC3HDAC2HTTLMNA | |
| Niacinamide SCHEMBL8508202 | 0.79 | F7 (0.55) | HDAC1HDAC3HDAC2HTTEGFR | |
| Niacinamide SCHEMBL3281888 | 0.77 | F7 (0.52) | HDAC1HDAC3HDAC2HTTEGFR | |
| Niacinamide SCHEMBL8510801 | 0.76 | EGFR (0.42) | HDAC1HDAC3HTTCYP3A4EGFR | |
| SCHEMBL10483317 | 0.74 | HDAC1 (0.56) | HDAC1HDAC3HDAC2HTTLMNA | |
| SCHEMBL986023 | 0.73 | CYP2C19 (0.56) | HTTLMNACYP3A4SMN1; SMN2MEN1 | |
| SCHEMBL146921 | 0.72 | ALPL (0.60) | HDAC1HDAC3HDAC2LMNAHIF1A | |
| SCHEMBL11704133 | 0.72 | NPC1 (0.74) | HTTSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL11780084 | 0.71 | LMNA (0.58) | HDAC1HDAC3HDAC2HTTLMNA | |
| Adenine SCHEMBL15699 | 0.70 | F7 (0.56) | HDAC1HDAC3HDAC2EGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178113-A1 | Reagent for assaying creatine kinase | UNITIKA LTD. (JP) | 1986-04-16 | — | — | EP | disclosed |