Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | VEGFA | P15692 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10872615 | 1.00 | L3MBTL1 (0.47) | L3MBTL1POLBNPSR1TSHRMAPT | |
| SCHEMBL10872890 | 0.88 | TSHR (0.44) | L3MBTL1POLBNPSR1TSHRMAPT | |
| SCHEMBL10872887 | 0.88 | TSHR (0.44) | L3MBTL1POLBNPSR1TSHRMAPT | |
| SCHEMBL10873083 | 0.85 | GAA (0.43) | POLBNPSR1TSHRMAPTALDH1A1 | |
| SCHEMBL10873080 | 0.85 | GAA (0.43) | POLBNPSR1TSHRMAPTALDH1A1 | |
| SCHEMBL10873376 | 0.82 | SMN1; SMN2 (0.49) | L3MBTL1POLBTSHRALDH1A1KDM4E | |
| SCHEMBL10873373 | 0.82 | SMN1; SMN2 (0.49) | L3MBTL1POLBTSHRALDH1A1KDM4E | |
| SCHEMBL9685245 | 0.80 | MAPT (0.58) | L3MBTL1POLBNPSR1TSHRMAPT | |
| SCHEMBL10873229 | 0.77 | TSHR (0.39) | L3MBTL1POLBNPSR1TSHRMAPT | |
| SCHEMBL10873225 | 0.77 | TSHR (0.39) | L3MBTL1POLBNPSR1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194484-A2 | Synthesis of 1-(2-amino-2-phenylethyl)-2-piperidinones | PENNWALT CORPORATION (US) | 1986-09-17 | — | — | EP | disclosed |