Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11181571 | 0.79 | CYP2D6 (0.53) | ADRB2ADRB1ADRB3CYP2D6MTNR1A | |
| SCHEMBL10761611 | 0.75 | ADRB2 (0.54) | ADRB2ADRB1ADRB3CYP2D6MTNR1A | |
| SCHEMBL3826640 | 0.75 | LMNA (0.45) | MTNR1AMTNR1BMEN1CYP1A2KMT2A | |
| SCHEMBL28393357 | 0.75 | ADRB2 (0.48) | ADRB2ADRB1ADRB3CYP2D6 | |
| Hydrochloric Acid SCHEMBL5266256 | 0.73 | ALDH1A1 (0.45) | MTNR1AMTNR1BMEN1CYP1A2KMT2A | |
| SCHEMBL5382881 | 0.72 | CSNK1E (0.53) | ADRB2ADRB1ADRB3CYP2D6 | |
| SCHEMBL11180497 | 0.72 | CASR (0.50) | ADRB2ADRB1ADRB3CYP2D6MTNR1A | |
| SCHEMBL11187559 | 0.72 | KMT2A (0.49) | ADRB2ADRB1ADRB3CYP2D6MTNR1A | |
| SCHEMBL11187665 | 0.72 | ADRB2 (0.44) | ADRB2ADRB1ADRB3CYP2D6MEN1 | |
| SCHEMBL11191954 | 0.71 | ADRB3 (0.47) | ADRB2ADRB1ADRB3CYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0192829-A1 | Amino propanol derivatives, process for their preparation, medicines containing these compounds and intermediates | Roche Diagnostics GmbH (DE) | 1986-09-03 | — | — | EP | disclosed |