Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PRCP | P42785 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5579737 | 0.86 | TACR1 (0.43) | KDM1ARCOR1KDM4ELMNAHSD17B10 | |
| SCHEMBL18831935 | 0.85 | KDM1A (0.51) | KDM1ARCOR1KDM4ELMNAHSD17B10 | |
| SCHEMBL18831932 | 0.85 | KDM1A (0.51) | KDM1ARCOR1KDM4ELMNAHSD17B10 | |
| SCHEMBL29859911 | 0.84 | MALT1 (0.51) | TACR1FKBP4 | |
| SCHEMBL30225406 | 0.82 | AKT1 (0.45) | TACR1CTSLCTSKFKBP4 | |
| SCHEMBL7586649 | 0.82 | OPRM1 (0.47) | TACR1FKBP4 | |
| SCHEMBL30561151 | 0.82 | OPRM1 (0.47) | TACR1FKBP4 | |
| SCHEMBL11464122 | 0.81 | KDM4E (0.71) | KDM1ARCOR1KDM4ELMNAHSD17B10 | |
| Acetic Acid SCHEMBL31076322 | 0.81 | AKT1 (0.47) | TACR1FKBP4 | |
| SCHEMBL5704652 | 0.80 | FKBP4 (0.48) | TACR1FKBP4MMP1MMP3SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153413-B2 | High alkaline protease and use thereof | JAPAN AGENCY FOR MARINE-EARTH SCIENCE AND TECHNOLOGY (JP) | 2012-04-10 | — | — | US | disclosed |
| US-20110045570-A1 | NOVEL HIGH ALKALINE PROTEASE AND USE THEREOF | JAPAN AGENCY FOR MARINE-EARTH SCIENCE AND TECH. (JP) | 2011-02-24 | — | — | US | disclosed |