SCHEMBL29859911

SCHEMBL29859911

CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)Nc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ MALT1 Q9UDY8 1/20 0.51
▸ CMA1 P23946 10/20 0.46
▸ EPHA2 P29317 2/20 0.45
▸ TACR1 P25103 1/20 0.44
▸ FKBP4 Q02790 1/20 0.44
▸ OPRM1 P35372 2/20 0.42
▸ OPRK1 P41145 2/20 0.42
▸ AKT1 P31749 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29860115 0.89 AKT1 (0.50) MALT1CMA1TACR1AKT1
SCHEMBL5579737 0.89 TACR1 (0.43) TACR1FKBP4
SCHEMBL6746799 0.89 CMA1 (0.49) CMA1
SCHEMBL30561151 0.85 OPRM1 (0.47) TACR1FKBP4OPRM1OPRK1
SCHEMBL7586649 0.85 OPRM1 (0.47) TACR1FKBP4OPRM1OPRK1
SCHEMBL18619572 0.84 MALT1 (0.64) MALT1CMA1EPHA2
SCHEMBL18621052 0.84 MALT1 (0.64) MALT1CMA1EPHA2
SCHEMBL22811073 0.84 MALT1 (0.64) MALT1CMA1EPHA2
SCHEMBL22209365 0.84 MALT1 (0.64) MALT1CMA1EPHA2
SCHEMBL1087489 0.84 KDM1A (0.50) TACR1FKBP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12540944-B2 Recombinant amebocyte clotting factors and uses thereof CHARLES RIVER LABORATORIES, INC. (US) 2026-02-03 — — US disclosed
US-20250085289-A1 RECOMBINANT AMEBOCYTE CLOTTING FACTORS AND USES THEREOF CHARLES RIVER LABORATORIES, INC. 2025-03-13 — — US disclosed
US-12158471-B2 Recombinant amebocyte lysate and uses thereof CHARLES RIVER LABORATORIES, INC. (US) 2024-12-03 — — US disclosed
US-20240125789-A1 HYBRID AMEBOCYTE LYSATE AND USES THEREOF CHARLES RIVER LABORATORIES, INC. (US) 2024-04-18 — — US disclosed
EP-4291648-A1 HYBRID AMEBOCYTE LYSATE AND USES THEREOF Charles River Laboratories, Inc. (US) 2023-12-20 — — EP disclosed
US-20230258647-A1 HYBRID AMEBOCYTE LYSATE AND USES THEREOF JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2023-08-17 — — US disclosed
WO-2022174082-A1 HYBRID AMEBOCYTE LYSATE AND USES THEREOF CHARLES RIVER LABORATORIES, INC. (US) 2022-08-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12540944-B2 Recombinant amebocyte clotting factors and uses thereof F13B, FGB, F5 MALT1 3388/4885CMA1 2267/4885EPHA2 2681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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