Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 4/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5631220 | 0.76 | MEN1 (0.52) | OPRK1KMT2AMEN1CNR1ADRB1 | |
| SCHEMBL6767270 | 0.75 | KMT2A (0.59) | OPRK1KMT2AMEN1ADRB1MITF | |
| SCHEMBL5099392 | 0.74 | SIGMAR1 (0.47) | KMT2AMEN1CNR1MAPK1HTT | |
| Hydrochloric Acid SCHEMBL11751277 | 0.72 | ESR1 (0.45) | OPRK1ADRA2CADRB1ADRB2 | |
| SCHEMBL5099387 | 0.71 | CNR1 (0.48) | KMT2AMEN1CNR1ACLYTAAR1 | |
| SCHEMBL6337215 | 0.71 | GPR84 (0.48) | KMT2AMEN1CNR1MAPK1HTT | |
| SCHEMBL28650574 | 0.69 | TAAR1 (0.55) | KMT2AMEN1CNR1MAPK1HTT | |
| SCHEMBL6212874 | 0.68 | ADRA2C (0.51) | ADRA2CLMNAMAPK1HTTNPSR1 | |
| SCHEMBL585759 | 0.68 | IDO1 (0.52) | CNR1ACLYMAPK1HTT | |
| SCHEMBL7460986 | 0.68 | ADRA2C (0.51) | ADRA2CLMNAMAPK1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0104888-B1 | PROCESS FOR PREPARING 2-HYDROXY-2-PHENYLETHYLAMINES | ELI LILLY AND COMPANY (US) | 1986-10-15 | — | — | EP | disclosed |
| EP-0104888-A1 | Process for preparing 2-hydroxy-2-phenylethylamines | ELI LILLY AND COMPANY (US) | 1984-04-04 | — | — | EP | disclosed |