Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8176237 | 0.85 | ALDH1A1 (0.58) | ALDH1A1GPR35L3MBTL1TSHRTP53 | |
| Methane SCHEMBL28281859 | 0.84 | ALDH1A1 (0.57) | ALDH1A1GPR35L3MBTL1TSHRTP53 | |
| SCHEMBL11819145 | 0.82 | ALDH1A1 (0.64) | ALDH1A1L3MBTL1TSHRTP53MAPK1 | |
| SCHEMBL9805745 | 0.80 | ALDH1A1 (0.50) | ALDH1A1GPR35L3MBTL1TSHRTP53 | |
| SCHEMBL28462224 | 0.80 | ALDH1A1 (0.53) | ALDH1A1GPR35L3MBTL1TSHRTP53 | |
| SCHEMBL1678369 | 0.80 | GPR35 (0.50) | ALDH1A1GPR35L3MBTL1TSHRTP53 | |
| SCHEMBL7808225 | 0.79 | ALDH1A1 (0.60) | ALDH1A1GPR35L3MBTL1TSHRTP53 | |
| SCHEMBL792021 | 0.79 | ALDH1A1 (0.62) | ALDH1A1L3MBTL1TSHRTP53SMN1; SMN2 | |
| SCHEMBL28566572 | 0.79 | ALDH1A1 (0.49) | ALDH1A1GPR35L3MBTL1TSHRTP53 | |
| SCHEMBL4802337 | 0.78 | HSD17B10 (0.60) | ALDH1A1TSHRTP53SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023234187-A1 | METHOD FOR PRODUCING ORGANIC COPPER COMPOUND | シンクレスト株式会社 | 2023-12-07 | — | — | WO | disclosed |
| WO-2023120645-A1 | ORGANIC ZINC COMPOUND AND PRODUCTION METHOD FOR ORGANIC ZINC COMPOUND | シンクレスト株式会社 | 2023-06-29 | — | — | WO | disclosed |
| WO-2023120647-A1 | ORGANIC COPPER COMPOUND, AND METHOD FOR PRODUCING ORGANIC COPPER COMPOUND | シンクレスト株式会社 | 2023-06-29 | — | — | WO | disclosed |
| US-10294218-B2 | 4,6-disubstituted aminopyrimidine derivatives have anti-HIV activity | VIROSTATICS SRL (IT) | 2019-05-21 | — | — | US | disclosed |
| CN-104822380-B | The novel disubstituted aminopyridine derivative of 4,6- | 维罗斯塔蒂克斯公司 | 2019-01-01 | — | — | CN | disclosed |
| EP-2887943-B1 | NOVEL 4,6-DISUBSTITUTED AMINOPYRIMIDINE DERIVATIVES | VIROSTATICS SRL (IT) | 2017-12-06 | — | — | EP | disclosed |
| EP-2887943-B1 | NOVEL 4,6-DISUBSTITUTED AMINOPYRIMIDINE DERIVATIVES | VIROSTATICS SRL (IT) | 2017-12-06 | — | — | EP | disclosed |
| US-20170204084-A1 | NOVEL 4,6-DISUBSTITUTED AMINOPYRIMIDINE DERIVATIVES HAVE ANTI-HIV ACTIVITY | VIROSTATICS SRL (IT) | 2017-07-20 | — | — | US | disclosed |
| US-20170204084-A1 | NOVEL 4,6-DISUBSTITUTED AMINOPYRIMIDINE DERIVATIVES HAVE ANTI-HIV ACTIVITY | VIROSTATICS SRL (IT) | 2017-07-20 | — | — | US | disclosed |
| US-9617225-B2 | 4,6-disubstituted aminopyrimidine derivatives have anti-HIV activity | VIROSTATICS SRL (IT) | 2017-04-11 | — | — | US | disclosed |
| US-9329475-B2 | Positive photosensitive resin composition, photosensitive resin film prepared by using the same, and display device | CHEIL INDUSTRIES INC. (KR) | 2016-05-03 | — | — | US | disclosed |
| CN-104822380-A | Novel 4,6-disubstituted aminopyrimidine derivatives | VIROSTATICS SRL | 2015-08-05 | — | — | CN | disclosed |
| EP-2887943-A1 | NOVEL 4,6-DISUBSTITUTED AMINOPYRIMIDINE DERIVATIVES | Virostatics Srl (IT) | 2015-07-01 | — | — | EP | disclosed |
| US-20150111153-A1 | Positive Photosensitive Resin Composition, Photosensitive Resin Film Prepared by Using the Same, and Display Device | CHEIL INDUSTRIES INC. (KR) | 2015-04-23 | — | — | US | disclosed |
| US-20140057911-A1 | NOVEL 4,6-DISUBSTITUTED AMINOPYRIMIDINE DERIVATIVES HAVING BOTH AROMATIC AND HALOGENIC SUBSTITUENTS | VIROSTATICS SRL (IT) | 2014-02-27 | — | — | US | disclosed |
| WO-2014031937-A1 | NOVEL 4,6-DISUBSTITUTED AMINOPYRIMIDINE DERIVATIVES | VIROSTATICS SRL (IT) | 2014-02-27 | — | — | WO | disclosed |
| US-20140057911-A1 | NOVEL 4,6-DISUBSTITUTED AMINOPYRIMIDINE DERIVATIVES HAVING BOTH AROMATIC AND HALOGENIC SUBSTITUENTS | VIROSTATICS SRL (IT) | 2014-02-27 | — | — | US | disclosed |
| EP-0100920-B1 | PHOTOSENSITIVE COMPOSITION AND PATTERN FORMING PROCESS USING SAME | HITACHI, LTD. (JP) | 1986-07-16 | — | — | EP | disclosed |
| US-4510226-A | Photosensitive composition and pattern forming process using same | HITACHI, LTD. (JP) | 1985-04-09 | — | — | US | disclosed |
| EP-0100920-A1 | Photosensitive composition and pattern forming process using same | HITACHI, LTD. (JP) | 1984-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10294218-B2 | 4,6-disubstituted aminopyrimidine derivatives have anti-HIV activity | DUT, UMPS, DPYD | ALDH1A1 872/4885GPR35 3857/4885L3MBTL1 1311/4885 |
| US-20140057911-A1 | NOVEL 4,6-DISUBSTITUTED AMINOPYRIMIDINE DERIVATIVES HAVING BOTH AROMATIC AND HALOGENIC SUBSTITUENTS | DPYD, ABL1, BRD4 | ALDH1A1 507/4885GPR35 3496/4885L3MBTL1 1612/4885 |
| US-20170204084-A1 | NOVEL 4,6-DISUBSTITUTED AMINOPYRIMIDINE DERIVATIVES HAVE ANTI-HIV ACTIVITY | UMPS, DPYD, DUT | ALDH1A1 942/4885GPR35 3858/4885L3MBTL1 1683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.