Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.44 |
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA7 | P43166 | 5/20 | 0.44 |
| ▸ | CA9 | Q16790 | 5/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31392618 | 0.74 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CMEN1KMT2A | |
| SCHEMBL10790009 | 0.72 | ADRB2 (0.58) | ADRA2AADRA2BADRA2CMEN1KMT2A | |
| SCHEMBL31392616 | 0.69 | ADRA2A (0.47) | ADRA2AADRA2BADRA2CMEN1KMT2A | |
| SCHEMBL5933090 | 0.67 | LMNA (0.45) | NLRP3MIFTSHRLMNAALDH1A1 | |
| SCHEMBL1376178 | 0.66 | CA1 (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2987382 | 0.66 | ADRA2A (0.43) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7224454 | 0.65 | TSHR (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29993800 | 0.64 | CA12 (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7150196 | 0.64 | TAAR1 (0.54) | ADRA2AADRA2BADRA2CMEN1KMT2A | |
| SCHEMBL9150253 | 0.64 | CYP3A4 (0.42) | ADRA2AADRA2BADRA2CMIFMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0104888-B1 | PROCESS FOR PREPARING 2-HYDROXY-2-PHENYLETHYLAMINES | ELI LILLY AND COMPANY (US) | 1986-10-15 | — | — | EP | disclosed |
| EP-0104888-A1 | Process for preparing 2-hydroxy-2-phenylethylamines | ELI LILLY AND COMPANY (US) | 1984-04-04 | — | — | EP | disclosed |