SCHEMBL10877933

SCHEMBL10877933

CC(C)(C)C(=O)C(Br)C(=O)Nc1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.65
HSP90AA1 P07900 2/20 0.65
GPR55 Q9Y2T6 1/20 0.65
ALDH1A1 P00352 5/20 0.50
MEN1 O00255 5/20 0.50
KMT2A Q03164 5/20 0.50
GAA P10253 2/20 0.50
ATM Q13315 2/20 0.50
POLB P06746 2/20 0.50
LMNA P02545 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50
NAPRT Q6XQN6 1/20 0.47
HSD17B10 Q99714 1/20 0.47
SMN1; SMN2 Q16637 4/20 0.46
HPGD P15428 2/20 0.46
HTT P42858 2/20 0.46
TP53 P04637 1/20 0.45
EPHX1 P07099 1/20 0.45
TSHR P16473 1/20 0.45
EPHX2 P34913 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9068980 0.85 POLB (0.61) MAPTHSP90AA1GPR55ALDH1A1MEN1
SCHEMBL6846422 0.81 MAPT (0.62) MAPTHSP90AA1GPR55ALDH1A1MEN1
SCHEMBL9157991 0.81 POLB (0.57) MAPTHSP90AA1GPR55ALDH1A1MEN1
SCHEMBL9158000 0.81 POLB (0.57) MAPTHSP90AA1GPR55ALDH1A1MEN1
SCHEMBL27922300 0.80 MAPT (0.57) MAPTHSP90AA1GPR55ALDH1A1MEN1
SCHEMBL926327 0.79 ALDH1A1 (0.59) MAPTHSP90AA1GPR55ALDH1A1MEN1
SCHEMBL10698727 0.79 MAPT (1.00) MAPTHSP90AA1GPR55ALDH1A1MEN1
SCHEMBL628621 0.77 ALDH1A1 (0.61) MAPTHSP90AA1GPR55ALDH1A1MEN1
SCHEMBL1800895 0.77 POLB (0.61) MAPTHSP90AA1GPR55ALDH1A1MEN1
SCHEMBL27271508 0.76 ALDH1A1 (0.66) MAPTHSP90AA1GPR55ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0034950-B1 HETEROCYCLIC 4- AND 6-EQUIVALENT PHOTOGRAPHIC COLOUR COUPLERS AND PHOTOGRAPHIC MATERIALS AND DEVELOPER COMPOSITIONS CONTAINING THEM EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1986-01-08 EP disclosed
US-4338393-A COLOR PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1982-07-06 US disclosed
US-4314023-A AZO-METHINE DYES KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1982-02-02 US disclosed
EP-0034950-A2 Heterocyclic 4- and 6-equivalent photographic colour couplers and photographic materials and developer compositions containing them EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1981-09-02 EP disclosed