Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | GAA | P10253 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20203823 | 0.73 | ALDH1A1 (0.44) | ALDH1A1GAASMN1; SMN2KDM4EHTT | |
| SCHEMBL23571568 | 0.72 | POLB (0.55) | POLBALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL9910507 | 0.72 | AKR1C3 (0.43) | POLBALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL20204010 | 0.71 | POLB (0.54) | POLBALDH1A1GAAMAPTKDM4E | |
| SCHEMBL6935947 | 0.70 | GAA (0.56) | POLBALDH1A1GAAMAPTKDM4E | |
| SCHEMBL20204005 | 0.70 | POLB (0.49) | POLBALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL10858393 | 0.70 | HTR1A (0.46) | POLBALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL23571322 | 0.70 | POLB (0.52) | POLBALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL3152711 | 0.69 | PTK2 (0.55) | POLBALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL247482 | 0.69 | GAA (0.51) | POLBALDH1A1GAASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61151177-A | — | — | None | — | — | JP | disclosed |
| JP-S61151177-A | NOVEL HYDRAZIDE DERIVATIVE AND DRUG CONTAINING SAME AS ACTIVE INGREDIENT | OTA SEIYAKU KK | 1986-07-09 | — | — | JP | disclosed |