Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCNA | P12004 | 13/20 | 0.69 |
| ▸ | LIG1 | P18858 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | THRA | P10827 | 3/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | GABRP | O00591 | 1/20 | 0.53 |
| ▸ | GABRD | O14764 | 1/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.53 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.53 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.53 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10878720 | 1.00 | PCNA (0.69) | PCNALIG1THRBLMNAMEN1 | |
| SCHEMBL7596233 | 0.88 | PCNA (0.66) | PCNALIG1THRBLMNAMEN1 | |
| SCHEMBL30354491 | 0.86 | THRB (0.68) | PCNATHRBLMNAMEN1KMT2A | |
| SCHEMBL27988679 | 0.86 | THRB (0.68) | PCNATHRBLMNAMEN1KMT2A | |
| SCHEMBL27940335 | 0.85 | THRB (0.67) | PCNATHRBLMNAMEN1KMT2A | |
| SCHEMBL1115191 | 0.84 | PCNA (0.52) | PCNALIG1THRBLMNAMEN1 | |
| SCHEMBL188398 | 0.84 | FOLH1 (0.49) | PCNAMEN1KMT2APPARG | |
| SCHEMBL188399 | 0.84 | FOLH1 (0.49) | PCNAMEN1KMT2APPARG | |
| SCHEMBL28520123 | 0.82 | FOLH1 (0.48) | PCNAMEN1KMT2APPARG | |
| SCHEMBL5177568 | 0.82 | PCNA (0.58) | PCNALIG1THRBLMNATHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0073865-B1 | DERIVATIVES OF IODOTHYRONINE COMPOUNDS AND THEIR USE IN AN ASSAY FOR THE FREE IODOTHYRONINE COMPOUNDS | AMERSHAM INTERNATIONAL plc (GB) | 1986-01-29 | — | — | EP | claimed |
| CN-102858156-B | Methods, compositions and kits for providing therapy | ASHUR-FABIAN OSNAT (IL) | 2015-09-23 | — | — | CN | disclosed |
| CN-102858156-A | Methods, compositions and kits for providing therapy | ASHUR-FABIAN OSNAT | 2013-01-02 | — | — | CN | disclosed |